WHO Model List of Essential Medicines (2021) | List | Annotated Medicine and Device Lists

01. ANAESTHETICS, PREOPERATIVE MEDICINES AND MEDICAL GASES

Medicine	Pharmaceutical form type	Composition
halothane	Inhalation	N/A
isoflurane	Inhalation	N/A
nitrous oxide	Inhalation	N/A
oxygen	Inhalation (medicine gas)	N/A

Medicine	Pharmaceutical form type	Composition
ketamine	Injection	50 mg (as hydrochloride)/mL in 10-mL vial
propofol	Injection	10 mg/mL
propofol	Injection	20 mg/mL

Medicine	Pharmaceutical form type	Composition	Observation
bupivacaine	Injection	0.25% (hydrochloride) in vial	e
bupivacaine	Injection	0.5% (hydrochloride) in vial	e
bupivacaine	Injection for spinal anaesthesia	0.5% (hydrochloride) in 20-ml ampoule to be mixed with 7.5% glucose solution	e
lidocaine	Injection	1% (hydrochloride) in vial	e
lidocaine	Injection	2% (hydrochloride) in vial	e
lidocaine	Injection for spinal anaesthesia	5% (hydrochloride) in 2-ml ampoule to be mixed with 7.5% glucose solution	e
lidocaine	Topical forms	2% to 4% (hydrochloride)	e
lidocaine + epinephrine (adrenaline)	Dental cartridge	2% (hydrochloride) + epinephrine 1:80 000
lidocaine + epinephrine (adrenaline)	Injection	1% (hydrochloride or sulfate) + epinephrine 1:200 000 in vial
lidocaine + epinephrine (adrenaline)	Injection	2% (hydrochloride or sulfate) + epinephrine 1:200 000 in vial

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
ephedrine	Injection	30 mg (hydrochloride)/ml in 1-ml ampoule

Medicine	Pharmaceutical form type	Composition	Observation
atropine	Injection	1 mg (sulfate) in 1-ml ampoule
midazolam	Injection	1 mg/ml	e
midazolam	Oral liquid	2 mg/ml	c2 e
midazolam	Tablet	15 mg	e
midazolam	Tablet	7.5 mg	e
morphine	Injection	10 mg (sulfate or hydrochloride) in 1-ml ampoule

Medicine	Pharmaceutical form type	Composition	Observation
oxygen	Inhalation (medicine gas)	N/A

02. MEDICINES FOR PAIN AND PALLIATIVE CARE

Medicine	Pharmaceutical form type	Composition	Observation
acetylsalicylic acid	Suppository	120 mg
acetylsalicylic acid	Suppository	50 mg to 150 mg	c1
acetylsalicylic acid	Suppository	60 mg
acetylsalicylic acid	Tablet	100 mg to 500 mg	c1
acetylsalicylic acid	Tablet	325 mg
acetylsalicylic acid	Tablet	500 mg
ibuprofen	Oral liquid	200 mg/5 mL	a
ibuprofen	Tablet	200 mg	a
ibuprofen	Tablet	400 mg	a
ibuprofen	Tablet	600 mg
paracetamol	Oral liquid	120 mg/5 mL
paracetamol	Oral liquid	125 mg/5 ml
paracetamol	Suppository	100 mg
paracetamol	Tablet	100 mg to 500 mg
paracetamol	Tablet	325 mg
paracetamol	Tablet	500 mg

Medicine	Pharmaceutical form type	Composition
codeine	Tablet	30 mg (phosphate)
fentanyl	Patch	100 mcg/hr
fentanyl	Patch	12 mcg/hr
fentanyl	Patch	25 mcg/hr
fentanyl	Patch	50 mcg/hr
fentanyl	Patch	75 mcg/hr
morphine	Granules (modified release) (to mix with water)	100 mg
morphine	Granules (modified release) (to mix with water)	20 mg
morphine	Granules (modified release) (to mix with water)	200 mg
morphine	Granules (modified release) (to mix with water)	30 mg
morphine	Granules (modified release) (to mix with water)	60 mg
morphine	Injection	10 mg (sulfate or hydrochloride) in 1-ml ampoule
morphine	Oral liquid	10 mg (hydrochloride or sulfate)/5 ml
morphine	Tablet (immediate release)	10 mg
morphine	Tablet (prolonged release)	10 mg (morphine sulfate)
morphine	Tablet (prolonged release)	10 mg to 200 mg
morphine	Tablet (prolonged release)	100 mg (morphine sulfate)
morphine	Tablet (prolonged release)	15 mg (morphine sulfate)
morphine	Tablet (prolonged release)	200 mg (morphine sulfate)
morphine	Tablet (prolonged release)	30 mg (morphine sulfate)
morphine	Tablet (prolonged release)	60 mg (morphine sulfate)

Complementary list

Medicine	Pharmaceutical form type	Composition
methadone	Concentrate for oral liquid	10 mg/ml (hydrochloride)
methadone	Concentrate for oral liquid	5 mg/ml (hydrochloride)
methadone	Oral liquid	10 mg/5 ml (hydrochloride)
methadone	Oral liquid	5 mg/5 ml (hydrochloride)
methadone	Tablet	10mg
methadone	Tablet	5mg

Medicine	Pharmaceutical form type	Composition	Observation
amitriptyline	Tablet	10 mg
amitriptyline	Tablet	25 mg
amitriptyline	Tablet	75 mg
cyclizine	Injection	50 mg/ml
cyclizine	Tablet	50 mg
dexamethasone	Injection	4 mg/mL in 1-mL ampoule (as disodium phosphate salt)
dexamethasone	Oral liquid	2 mg/5 mL
dexamethasone	Tablet	2 mg
dexamethasone	Tablet	4 mg
diazepam	Injection	5 mg/mL
diazepam	Oral liquid	2 mg/5 mL
diazepam	Rectal solution	10 mg
diazepam	Rectal solution	2.5 mg
diazepam	Rectal solution	5 mg
diazepam	Tablet	10 mg
diazepam	Tablet	5 mg
docusate sodium	Capsule	100 mg
docusate sodium	Oral liquid	50 mg/5 ml
fluoxetine	Solid oral dosage form	20 mg (as hydrochloride)	a
haloperidol	Injection	5 mg/mL in 1-mL ampoule
haloperidol	Oral liquid	2 mg/mL
haloperidol	Solid oral dosage form	0.5 mg
haloperidol	Solid oral dosage form	2 mg
haloperidol	Solid oral dosage form	5 mg
hyoscine butylbromide	Injection	20 mg/ml in 1-mL ampoule
hyoscine hydrobromide	Injection	400 mcg/mL	c1
hyoscine hydrobromide	Injection	600 mcg/mL	c1
hyoscine hydrobromide	Transdermal patches	1 mg/72 hours	c1
lactulose	Oral liquid	3.1-3.7 g/5 ml	c1
loperamide	Solid oral dosage form	2mg
metoclopramide	Injection	5 mg (hydrochloride)/mL in 2-mL ampoule
metoclopramide	Oral liquid	5 mg/5 mL
metoclopramide	Tablet	10 mg (hydrochloride)
midazolam	Injection	1 mg/ml
midazolam	Injection	5 mg/mL
midazolam	Oral liquid	2 mg/ml	c1
midazolam	Tablet	15 mg
midazolam	Tablet	7.5 mg
ondansetron	Injection	2 mg base/ml in 2-ml ampoule (as hydrochloride)	a c1
ondansetron	Oral liquid	4 mg base/5 ml	a c1
ondansetron	Solid oral dosage form	Eq 4 mg base	a c1
ondansetron	Solid oral dosage form	Eq 8 mg base	a c1
senna	Oral liquid	7.5 mg/5 ml

03. ANTIALLERGICS AND MEDICINES USED IN ANAPHYLAXIS

Medicine	Pharmaceutical form type	Composition	Observation
dexamethasone	Injection	4 mg/mL in 1-mL ampoule (as disodium phosphate salt)
epinephrine (adrenaline)	Injection	1 mg (as hydrochloride or hydrogen tartrate) in 1-ml ampoule
hydrocortisone	Powder for injection	100 mg (as sodium succinate) in vial
loratadine	Oral liquid	1mg/ml	e
loratadine	Tablet	10 mg	e
prednisolone	Oral liquid	5 mg/mL	c2 e
prednisolone	Tablet	25 mg	e
prednisolone	Tablet	5 mg	e

04. ANTIDOTES AND OTHER SUBSTANCES USED IN POISONINGS

Medicine	Pharmaceutical form type	Composition	Observation
charcoal, activated	Powder	N/A

Medicine	Pharmaceutical form type	Composition	Observation
acetylcysteine	Injection	200 mg/ml in 10-ml ampoule
acetylcysteine	Oral liquid	10%	c2
acetylcysteine	Oral liquid	20%	c2
atropine	Injection	1 mg (sulfate) in 1-ml ampoule
calcium gluconate	Injection	100 mg/mL in 10-mL ampoule
methylthioninium chloride (methylene blue)	Injection	10 mg/ml in 10-ml ampoule
naloxone	Injection	400 mcg (hydrochloride) in 1-mL ampoule
penicillamine	Solid oral dosage form	250 mg
potassium ferric hexacyano-ferrate(II) - 2H20 (Prussian blue)	Powder for oral administration	N/A
sodium nitrite	Injection	30 mg/mL in 10-mL ampoule
sodium thiosulfate	Injection	250 mg/mL in 50-mL ampoule

Complementary list

Medicine	Pharmaceutical form type	Composition
deferoxamine	Powder for injection	500 mg (mesilate) in vial
dimercaprol	Injection in oil	50 mg/mL in 2-mL ampoule
fomepizole	Injection	5 mg/ml (sulfate) in 20 ml ampoule or 1 g/ ml (base) in 1.5 ml ampoule
sodium calcium edetate	Injection	200 mg/ml in 5-ml ampoule
succimer	Solid oral dosage form	100 mg

05. ANTICONVULSANTS/ ANTIEPILEPTICS

Medicine	Pharmaceutical form type	Composition	Observation
carbamazepine	Oral liquid	100 mg/5 ml
carbamazepine	Tablet (chewable)	100 mg
carbamazepine	Tablet (chewable)	200 mg
carbamazepine	Tablet (scored)	100 mg
carbamazepine	Tablet (scored)	200 mg
diazepam	Gel	5 mg/mL in 0.5-mL tubes
diazepam	Gel	5 mg/mL in 2-mL tubes
diazepam	Gel	5 mg/mL in 4-mL tubes
diazepam	Rectal solution	5 mg/mL in 0.5-mL tubes
diazepam	Rectal solution	5 mg/mL in 2-mL tubes
diazepam	Rectal solution	5 mg/mL in 4-mL tubes
lamotrigine	Tablet	100 mg
lamotrigine	Tablet	200 mg
lamotrigine	Tablet	25 mg
lamotrigine	Tablet	50 mg
lamotrigine	Tablet (buffered chewable, dispersible)	100 mg
lamotrigine	Tablet (buffered chewable, dispersible)	2 mg
lamotrigine	Tablet (buffered chewable, dispersible)	200 mg
lamotrigine	Tablet (buffered chewable, dispersible)	25 mg
lamotrigine	Tablet (buffered chewable, dispersible)	5 mg
lamotrigine	Tablet (buffered chewable, dispersible)	50 mg
lorazepam	Parenteral formulation	2 mg/ml in 1-ml ampoule	e
lorazepam	Parenteral formulation	4 mg/ml in 1-ml ampoule	e
magnesium sulfate	Injection	500 mg/mL in 10-mL ampoule
magnesium sulfate	Injection	500 mg/mL in 2-mL ampoule
midazolam	Injection	1 mg/ml
midazolam	Injection	10 mg/ml
midazolam	Solution for oromucosal administration	10 mg/ml
midazolam	Solution for oromucosal administration	5 mg/ml
phenobarbital	Injection	200 mg/mL (sodium)
phenobarbital	Oral liquid	15 mg/5 mL
phenobarbital	Tablet	100 mg
phenobarbital	Tablet	15 mg to 100 mg
phenobarbital	Tablet	16.2 mg
phenobarbital	Tablet	30 mg
phenobarbital	Tablet	32.4 mg
phenobarbital	Tablet	50 mg
phenobarbital	Tablet	60 mg
phenobarbital	Tablet	64.8 mg
phenobarbital	Tablet	97.2 mg
phenobarbitone	Tablet	15 mg
phenytoin	Injection	50 mg/mL in 5-mL vial (sodium salt)
phenytoin	Oral liquid	25 mg to 30 mg/5 mL
phenytoin	Oral liquid	25 mg/ 5 mL
phenytoin	Oral liquid	30 mg/5 mL
phenytoin	Solid oral dosage form	100 mg (sodium salt)
phenytoin	Solid oral dosage form	25 mg (sodium salt)
phenytoin	Solid oral dosage form	50 mg (sodium salt)
phenytoin	Tablet (chewable)	50 mg
valproic acid (sodium valproate)	Oral liquid	200 mg/5 ml
valproic acid (sodium valproate)	Tablet (crushable)	100 mg
valproic acid (sodium valproate)	Tablet (enteric-coated)	200 mg (sodium valproate)
valproic acid (sodium valproate)	Tablet (enteric-coated)	500 mg (sodium valproate)

Complementary list

Medicine	Pharmaceutical form type	Composition
ethosuximide	Capsule	250 mg
ethosuximide	Oral liquid	250 mg/5 ml
valproic acid (sodium valproate)	Injection	100 mg/ml in 10 ml ampoule
valproic acid (sodium valproate)	Injection	100 mg/ml in 4 ml ampoule

06. ANTI-INFECTIVE MEDICINES

Medicine	Pharmaceutical form type	Composition
albendazole	Tablet (chewable)	400 mg
ivermectin	Tablet (scored)	3 mg
levamisole	Tablet	150 mg (as hydrochloride)
levamisole	Tablet	50 mg (as hydrochloride)
mebendazole	Tablet (chewable)	100 mg
mebendazole	Tablet (chewable)	500 mg
niclosamide	Tablet (chewable)	500 mg
praziquantel	Tablet	150 mg
praziquantel	Tablet	600 mg
pyrantel	Oral liquid	50 mg (as embonate or pamoate)/ml
pyrantel	Tablet (chewable)	250 mg (as embonate or pamoate)

Medicine	Pharmaceutical form type	Composition
albendazole	Tablet (chewable)	400 mg
diethylcarbamazine	Tablet	100 mg (dihydrogen citrate)
diethylcarbamazine	Tablet	50 mg (dihydrogen citrate)
ivermectin	Tablet (scored)	3 mg

Medicine	Pharmaceutical form type	Composition	Observation
praziquantel	Tablet	600 mg
triclabendazole	Tablet	250 mg

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
oxamniquine	Capsule	250 mg
oxamniquine	Oral liquid	250 mg/5 ml

Medicine	Pharmaceutical form type	Composition	Observation

Complementary list

Medicine	Pharmaceutical form type	Composition
albendazole	Tablet (chewable)	400 mg
mebendazole	Tablet (chewable)	500 mg
praziquantel	Tablet	500 mg
praziquantel	Tablet	600 mg

This group includes antibiotics that have activity against a wide range of commonly encountered susceptible pathogens while also showing lower resistance potential than antibiotics in the other groups. Selected Access group antibiotics are recommended as essential first or second choice empiric treatment options for infectious syndromes reviewed by the EML Expert Committee and are listed as individual medicines on the Model Lists to improve access and promote appropriate use. They are essential antibiotics that should be widely available, affordable and quality assured.

Medicine	Pharmaceutical form type	Composition	Observation
amikacin	Injection	250 mg (as sulfate)/mL in 2-mL vial
amoxicillin	Injection	1 g
amoxicillin	Powder for injection	250 mg (as sodium) in vial
amoxicillin	Powder for injection	250 mg (as sodium) in vial
amoxicillin	Powder for injection	500 mg (as sodium) in vial
amoxicillin	Powder for oral liquid	125 mg (as trihydrate)/5 mL
amoxicillin	Powder for oral liquid	250 mg (as trihydrate)/5 mL	c2
amoxicillin	Solid oral dosage form	250 mg (as trihydrate)
amoxicillin	Solid oral dosage form	500 mg (as trihydrate)
amoxicillin	Tablet	1 g
amoxicillin + clavulanic acid	Oral liquid	125 mg amoxicillin + 31.25 mg clavulanic acid/5 ml
amoxicillin + clavulanic acid	Oral liquid	250 mg amoxicillin + 62.5 mg clavulanic acid/5 ml	c2
amoxicillin + clavulanic acid	Powder for injection	0.5 g (as sodium) + 0.1 g (as potassium salt) in vial
amoxicillin + clavulanic acid	Powder for injection	1g + 0.2g
amoxicillin + clavulanic acid	Tablet	500 mg (as trihydrate) + 125 mg (as potassium salt)
amoxicillin + clavulanic acid	Tablet	875mg + 125mg
ampicillin	Powder for injection	1 g (as sodium salt) in vial
ampicillin	Powder for injection	500 mg (as sodium salt) in vial
benzathine benzylpenicillin	Powder for injection	1.44 g benzylpenicillin (= 2.4 million IU) in 5-ml vial
benzathine benzylpenicillin	Powder for injection	900 mg benzylpenicillin (= 1.2 million IU) in 5-ml vial	c2
benzylpenicillin	Powder for injection	3 g (= 5 million IU) (sodium or potassium salt) in vial
benzylpenicillin	Powder for injection	600 mg (= 1 million IU) (sodium or potassium salt) in vial
cefalexin	Powder for reconstitution with water	125 mg/5 mL (anhydrous)	c2
cefalexin	Powder for reconstitution with water	250 mg/5 mL (anhydrous)	c2
cefalexin	Solid oral dosage form	250 mg (as monohydrate)
cefalexin	Tablet	500 mg
cefazolin	Powder for injection	1 g (as sodium salt) in vial	a e
chloramphenicol	Capsule	250 mg
chloramphenicol	Oily suspension for injection	0.5 g (as sodium succinate) / ml in 2 ml ampoule
chloramphenicol	Oral liquid	150 mg )as palmitate)/ 5 ml
chloramphenicol	Powder for injection	1 g (sodium succinate) in vial
clindamycin	Capsule	150 mg (as hydrochloride)
clindamycin	Injection	150 mg (as phosphate)/mL
clindamycin	Injection	600 mg
clindamycin	Injection	900 mg
clindamycin	Oral liquid	75 mg/5 mL (as palmitate)	c1
cloxacillin	Capsule	1 g (as sodium salt)	e
cloxacillin	Capsule	500 mg (as sodium salt)	e
cloxacillin	Powder for injection	500 mg (as sodium salt) in vial	e
cloxacillin	Powder for oral liquid	125 mg (as sodium salt)/5 mL	e
doxycycline	Oral liquid	25 mg/5 ml (anhydrous)	a c1
doxycycline	Oral liquid	50 mg/5 ml (anhydrous)	a c1
doxycycline	Powder for injection	100 mg	a c1
doxycycline	Solid oral dosage form	100 mg (as hyclate)	c1
doxycycline	Solid oral dosage form	50 mg (as hyclate)	a c1
gentamicin	Injection	10 mg (sulfate)/mL in 2-mL vial
gentamicin	Injection	40 mg (sulfate)/ml in 2-mL vial
metronidazole	Injection	500 mg in 100-mL vial
metronidazole	Oral liquid	200 mg (as benzoate)/5 mL
metronidazole	Suppository	1 g
metronidazole	Suppository	500 mg
metronidazole	Tablet	200 mg to 500 mg
nitrofurantoin	Oral liquid	25 mg/5 ml	c1
nitrofurantoin	Tablet	100 mg
phenoxymethylpenicillin	Powder for oral liquid	250 mg (as potassium salt)/5 ml
phenoxymethylpenicillin	Tablet	250 mg (as potassium salt)
phenoxymethylpenicillin	Tablet	500 mg (as potassium)
procaine benzylpenicillin	Powder for injection	1 g (=1 million IU) in vial
procaine benzylpenicillin	Powder for injection	3 g (=3 million IU) in vial
spectinomycin	Powder for injection	2 g (as hydrochloride) in vial
sulfamethoxazole + trimethoprim	Injection	80 mg + 16 mg/mL in 10-mL ampoule
sulfamethoxazole + trimethoprim	Injection	80 mg + 16 mg/mL in 5-mL ampoule
sulfamethoxazole + trimethoprim	Oral liquid	200 mg + 40 mg/5 mL
sulfamethoxazole + trimethoprim	Tablet	100 mg + 20 mg
sulfamethoxazole + trimethoprim	Tablet	400 mg + 80 mg
sulfamethoxazole + trimethoprim	Tablet	800 mg + 160 mg
trimethoprim	Oral liquid	50 mg/5 ml
trimethoprim	Tablet	100 mg
trimethoprim	Tablet	200 mg

This group includes antibiotic classes that have higher resistance potential and includes most of the highest priority agents among the Critically Important Antimicrobials for Human Medicine and/or antibiotics that are at relatively high risk of selection of bacterial resistance. These medicines should be prioritized as key targets of stewardship programs and monitoring. Selected Watch group antibiotics are recommended as essential first or second choice empiric treatment options for a limited number of specific infectious syndromes and are listed as individual medicines on the Model Lists.

Medicine	Pharmaceutical form type	Composition	Observation
azithromycin	Capsule	250 mg (anhydrous)
azithromycin	Capsule	500 mg (anhydrous)
azithromycin	Oral liquid	200 mg/5 mL
cefixime	Capsule	400 mg (as trihydrate)
cefixime	Solid oral dosage form	200 mg (as trihydrate)
cefixime	Suspension	100 mg/ 5 ml	c1
cefotaxime	Powder for injection	250 mg per vial (as sodium salt)
ceftriaxone	Powder for injection	1 g (as sodium salt) in vial
ceftriaxone	Powder for injection	2 g (as sodium) in vial
ceftriaxone	Powder for injection	250 mg (as sodium salt) in vial	a
cefuroxime	Injection	750 mg in vial
cefuroxime	Powder for injection	1.5 g (as sodium) in vial
cefuroxime	Powder for injection	250 mg (as sodium salt) in vial
ciprofloxacin	Oral liquid	250 mg/5 ml (anhydrous)	c2
ciprofloxacin	Solution for IV infusion	2 mg/ml (as hyclate)	c2
ciprofloxacin	Tablet	250 mg (as hydrochloride)
ciprofloxacin	Tablet	500 mg
clarithromycin	Powder for injection	500 mg in vial
clarithromycin	Powder for oral liquid	125-250 mg/5ml
clarithromycin	Solid oral dosage form	500 mg
piperacillin sodium + tazobactum sodium	Injection	2 g (as sodium) + 250 mg (as sodium) in vial
piperacillin sodium + tazobactum sodium	Injection	4.5 g
vancomycin	Capsule	125 mg (as hydrochloride)
vancomycin	Capsule	250 mg (as hydrochloride)
vancomycin	Injection	500 mg
vancomycin	Powder for injection	1 g

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
ceftazidime	Powder for injection	1 g (as pentahydrate) in vial
ceftazidime	Powder for injection	250 mg (as pentahydrate) in vial
meropenem	Injection	500 mg	a
meropenem	Powder for injection	1 g	a
vancomycin	Powder for injection	250 mg (as hydrochloride) in vial

Medicine	Pharmaceutical form type	Composition	Observation

Complementary list

Medicine	Pharmaceutical form type	Composition
cefiderocol	Powder for injection	1 g (as sulfate toxylate) in vial
ceftazidime + avibactam	Powder for injection	2 g + 0,5 g in vial
ceftazidime + avibactam	Powder for injection	2 g + 0,5 g in vial
colistin	Powder for injection	1 million I.U. (as colistemethate sodium) in vial
fosfomycin	Powder for injection	2 g (as sodium) in vial
fosfomycin	Powder for injection	4 g (as sodium) in vial
linezolid	injection for intravenous administration	2 mg/ ml in 300 ml bag
linezolid	Powder for oral liquid	100 mg/ 5 ml
linezolid	Tablet	400 mg
linezolid	Tablet	600 mg
meropenem + vaborbactam	Powder for injection	1 g + 1 g in vial
plazomicin	Injection	500 mg/ 10 ml
polymyxin B	Powder for injection	500.000 I.U. in vial

Medicines used in the treatment of leprosy should never be used except in combination. Combination therapy is essential to prevent the emergence of drug resistance. Colour coded blister packs (MDT blister packs) containing standard two medicine (paucibacillary leprosy) or three medicine (multibacillary leprosy) combinations for adult and childhood leprosy should be used. MDT blister packs can be supplied free of charge through WHO.

Medicine	Pharmaceutical form type	Composition
clofazimine	Capsule	100 mg
clofazimine	Capsule	50 mg
dapsone	Tablet	100 mg
dapsone	Tablet	25 mg
dapsone	Tablet	50 mg
rifampicin	Solid oral dosage form	150 mg
rifampicin	Solid oral dosage form	300 mg

WHO recommends and endorses the use of fixed-dose combinations and the development of appropriate new fixed-dose combinations, including modified dosage forms, non-refrigerated products and paediatric dosage forms of assured pharmaceutical quality.

Medicine	Pharmaceutical form type	Composition	Observation
ethambutol	Oral liquid	25 mg/ml	c2
ethambutol	Tablet	100 mg (hydrochloride)
ethambutol	Tablet (dispersible)	100 mg	c1
ethambutol + isoniazid + pyrazinamide + rifampicin	Tablet	275 mg + 75 mg + 400 mg + 150 mg
ethambutol + isoniazid + rifampicin	Tablet	275 mg + 75 mg + 150 mg
isoniazid	Oral liquid	50 mg/5 ml	c2
isoniazid	Tablet	300 mg
isoniazid	Tablet (dispersible)	100 mg	c1
isoniazid + pyrazinamide + rifampicin	Tablet (dispersible)	50 mg + 150 mg + 75 mg	c1
isoniazid + rifampicin	Tablet	150 mg + 300 mg
isoniazid + rifampicin	Tablet	75 mg + 150 mg
isoniazid + rifampicin	Tablet (dispersible)	50 mg + 75 mg	c1
isoniazid + rifapentine	Tablet (scored)	300 mg + 300 mg
moxifloxacin	Tablet	400 mg
pyrazinamide	Oral liquid	30 mg/ml	c2
pyrazinamide	Tablet	400 mg
pyrazinamide	Tablet	500 mg
pyrazinamide	Tablet (dispersible)	150 mg
rifabutin	Capsule	150 mg
rifampicin	Oral liquid	20 mg/ml	c2
rifampicin	Solid oral dosage form	150 mg
rifampicin	Solid oral dosage form	300 mg
rifapentine	Tablet	150 mg
rifapentine	Tablet	300 mg

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
amikacin	Powder for injection	100 mg (as sulfate) in vial
amikacin	Powder for injection	500 mg (as sulfate) in vial
amoxicillin + clavulanic acid	Oral liquid	250 mg amoxicillin + 62.5 mg clavulanic acid/5 ml	c1
amoxicillin + clavulanic acid	Tablet	500 mg (as trihydrate) + 125 mg (as potassium salt)
bedaquilina	Tablet	100 mg	a
bedaquilina	Tablet	20 mg
clofazimine	Capsule	100 mg
clofazimine	Capsule	50 mg
cycloserine	Solid oral dosage form	125 mg	c1
cycloserine	Solid oral dosage form	250 mg
delamanid	Tablet	50 mg	a
delamanid	Tablet (dispersible)	25 mg
ethionamide	Tablet	125 mg
ethionamide	Tablet	250 mg
ethionamide	Tablet (dispersible)	125 mg	c1
levofloxacin	Tablet	250 mg
levofloxacin	Tablet	500 mg
levofloxacin	Tablet	750 mg
levofloxacin	Tablet (dispersible)	100 mg	c1
linezolid	Powder for oral liquid	100 mg/ 5 ml
linezolid	Tablet	600 mg
linezolid	Tablet (dispersible)	150 mg	c1
meropenem	Injection	500 mg
meropenem	Powder for injection	1 g
moxifloxacin	Tablet	400 mg
moxifloxacin	Tablet (dispersible)	100 mg	c1
p-aminosalicylic acid	Granules	4 g in sachet
streptomycin	Powder for injection	1 g	c1

Medicine	Pharmaceutical form type	Composition	Observation
amphotericin B	Powder for injection	50 mg in vial
clotrimazole	Vaginal cream	1%
clotrimazole	Vaginal cream	10%
clotrimazole	Vaginal tablet	100 mg
clotrimazole	Vaginal tablet	500 mg
fluconazole	Capsule	50 mg
fluconazole	Injection	2 mg/mL in vial
fluconazole	Oral liquid	50 mg/5 mL
flucytosine	Capsule	250 mg
flucytosine	Infusion	2.5 g in 250 ml
griseofulvin	Oral liquid	125 mg/5 ml	c2
griseofulvin	Solid oral dosage form	125 mg
griseofulvin	Solid oral dosage form	250 mg
itraconazole	Capsule	100 mg
itraconazole	Oral liquid	10 mg/ ml
nystatin	Lozenge	100 000 IU
nystatin	Oral liquid	100 000 IU/ml	c1
nystatin	Oral liquid	50 mg/5 ml	c1
nystatin	Pessary	100 000 IU
nystatin	Tablet	100 000 IU
nystatin	Tablet	500 000 IU
voriconazol	Powder for injection	200 mg in vial
voriconazol	Powder for oral liquid	40 mg/ ml
voriconazol	Tablet	200 mg
voriconazol	Tablet	50 mg

Complementary list

Medicine	Pharmaceutical form type	Composition
micafungin	Powder for injection	100 mg (as sodium) in vial
micafungin	Powder for injection	50 mg (as sodium) in vial.
potassium iodide	Saturated solution	N/A

Medicine	Pharmaceutical form type	Composition	Observation
aciclovir	Oral liquid	200 mg/5 mL	e
aciclovir	Powder for injection	250 mg (as sodium salt) in vial	e
aciclovir	Tablet	200 mg	e

Based on current evidence and experience of use, medicines in the following three classes of antiretrovirals are included as essential medicines for treatment and prevention of HIV (prevention of mother-to-child transmission and post-exposure prophylaxis). The Committee emphasizes the importance of using these products in accordance with global and national guidelines. The Committee recommends and endorses the use of fixed-dose combinations and the development of appropriate new fixed-dose combinations, including modified dosage forms, non-refrigerated products and paediatric dosage forms of assured pharmaceutical quality. Scored tablets can be used in children and therefore can be considered for inclusion in the listing of tablets, provided adequate quality products are available.

Medicine	Pharmaceutical form type	Composition	Observation
abacavir (ABC)	Tablet	300 mg
lamivudine (3TC)	Oral liquid	50 mg/5 ml	c1
lamivudine (3TC)	Tablet	150 mg
tenofovir disoproxil fumarate	Tablet	300 mg
zidovudine (ZDV or AZT)	Capsule	250 mg
zidovudine (ZDV or AZT)	Oral liquid	50 mg/5 mL
zidovudine (ZDV or AZT)	Solution for IV infusion injection	10 mg/mL in 20-mL vial
zidovudine (ZDV or AZT)	Tablet	300 mg

Medicine	Pharmaceutical form type	Composition	Observation
efavirenz (EFV or EFZ)	Tablet	600 mg	a
nevirapine (NVP)	Oral liquid	50 mg/5 ml	a
nevirapine (NVP)	Tablet	200 mg	a
nevirapine (NVP)	Tablet (dispersible)	50 mg	a

Selection of protease inhibitor(s) from the Model List will need to be determined by each country after consideration of international and national treatment guidelines and experience. Ritonavir is recommended for use in combination as a pharmacological booster, and not as an antiretroviral in its own right. All other protease inhibitors should be used in boosted forms (e.g. with ritonavir).

Medicine	Pharmaceutical form type	Composition	Observation
atazanavir + ritonavir	Tablet (heat stable)	300 mg (as sulfate) + 100 mg
darunavir	Tablet	400 mg	a
darunavir	Tablet	600 mg	a
darunavir	Tablet	75 mg	a
darunavir	Tablet	800 mg	a
lopinavir + ritonavir (LPV/r)	Solid oral dosage form	40 mg + 10 mg	c1
lopinavir + ritonavir (LPV/r)	Tablet (heat stable)	100 mg + 25 mg
lopinavir + ritonavir (LPV/r)	Tablet (heat stable)	200 mg + 50 mg
ritonavir	Tablet (heat stable)	100 mg
ritonavir	Tablet (heat stable)	25 mg

Medicine	Pharmaceutical form type	Composition	Observation
dolutegravir	Tablet	50 mg	a
dolutegravir	Tablet (dispersible, scored)	10 mg
raltegavir	Granules for oral suspension	100 mg in sachet
raltegavir	Tablet	400 mg
raltegavir	Tablet (chewable)	25 mg

Medicine	Pharmaceutical form type	Composition	Observation
abacavir + lamivudine	Tablet (dispersible, scored)	120 mg (as sulfate) + 60 mg
dolutegravir + lamivudina + tenofovir	Tablet	50 mg + 300 mg + 300 mg (tenofovir disoproxil fumarate – equivalent to 245 mg tenofovir disoproxil)
efavirenz + emtricitabine + tenofovir	Tablet	600 mg + 200 mg + 300 mg
efavirenz + lamivudine + tenofovir	Tablet	400 mg + 300 mg + 300 mg
emtricitabine + tenofovir	Tablet	200 mg + 300 mg
lamivudine + zidovudine	Tablet	150 mg + 300 mg
lamivudine + zidovudine	Tablet (dispersible, scored)	30 mg + 60 mg	c1

Medicine	Pharmaceutical form type	Composition	Observation
isoniazid + pyridoxine + sulfamethoxazole + trimethoprim	Tablet (scored)	300 mg + 25 mg + 800 mg + 160 mg

Medicine	Pharmaceutical form type	Composition
ribavirin	injection for intravenous administration	1 g in 10-ml phosphate buffer solution
ribavirin	injection for intravenous administration	800 mg in 10-ml phosphate buffer solution
ribavirin	Solid oral dosage form	200 mg
ribavirin	Solid oral dosage form	400 mg
ribavirin	Solid oral dosage form	600 mg
valgancyclovir	Tablet	450mg

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
oseltamivir	Capsule	30 mg (as phosphate)
oseltamivir	Capsule	45 mg (as phosphate)
oseltamivir	Capsule	75 mg (as phosphate)
oseltamivir	Oral powder	12 mg/mL
valganciclovir	Powder for oral administration	50 mg/ ml	c1
valgancyclovir	Tablet	450mg	c1

Medicine	Pharmaceutical form type	Composition
entecavir	Oral liquid	0.05 mg/ ml
entecavir	Tablet	0.5 mg
entecavir	Tablet	1 mg
tenofovir disoproxil fumarate	Tablet	300 mg

Pangenotypic direct-acting antivirals should be considered as therapeutic alternatives for the purposes of selection and procurement at national level.

Medicine	Pharmaceutical form type	Composition
daclatasvir	Tablet	30 mg (as hydrochloride)
daclatasvir	Tablet	60 mg (as hydrochloride)
daclatasvir + sofosbuvir	Tablet	60 mg
glecaprevir + pibrentasvir	Granules	50 mg + 20 mg in sachet
glecaprevir + pibrentasvir	Tablet	100 mg + 40 mg
sofosbuvir	Tablet	200 mg
sofosbuvir	Tablet	400 mg
sofosbuvir + velpatasvir	Tablet	200 mg + 50 mg
sofosbuvir + velpatasvir	Tablet	400 mg + 100 mg.

Medicine	Pharmaceutical form type	Composition
dasabuvir	Tablet	250 mg
ledipasvir + sofosbuvir	Tablet	90 mg/ 400 mg
ombitasvir + paritaprevir + ritonavir	Tablet	12.5 mg + 75 mg + 50 mg

Medicine	Pharmaceutical form type	Composition
ribavirin	injection for intravenous administration	1 g in 10-ml phosphate buffer solution
ribavirin	injection for intravenous administration	800 mg in 10-ml phosphate buffer solution
ribavirin	Solid oral dosage form	200 mg
ribavirin	Solid oral dosage form	400 mg
ribavirin	Solid oral dosage form	600 mg

Complementary list

Medicine	Pharmaceutical form type	Composition
pegylated interferon	Injection	100 micrograms (peginterferon alfa-2b)
pegylated interferon	Injection	180 micrograms (peginterferon alfa-2a)
pegylated interferon	Injection	80 micrograms (peginterferon alfa-2b)

Medicine	Pharmaceutical form type	Composition	Observation
diloxanide	Tablet	500 mg (furoate)	a
metronidazole	Injection	500 mg in 100-mL vial	e
metronidazole	Oral liquid	200 mg (as benzoate)/5 mL	e
metronidazole	Tablet	200 mg to 500 mg	e
metronidazole	Tablet	250 mg
metronidazole	Tablet	500 mg

Medicine	Pharmaceutical form type	Composition
amphotericin B	Powder for injection	50 mg in vial
meglumine antimoniate	Injection	30%, equivalent to approximately 8.1% antimony (pentavalent) in 5-ml ampoule
miltefosine	Solid oral dosage form	10 mg
miltefosine	Solid oral dosage form	50 mg
paromomycin	Solution for intramuscular injection	750 mg of paromomycin base (as the sulfate)
sodium stibogluconate	Injection	100 mg/ml, 1 vial = 30 ml

Medicines for the treatment of P. falciparum malaria cases should be used in combination. The list currently recommends combinations according to treatment guidelines. The Committee recognizes that not all of these FDCs exist and encourages their development and rigorous testing. The Committee also encourages development and testing of rectal dosage formulations.

Medicine	Pharmaceutical form type	Composition	Observation
amodiaquine	Tablet	153 mg (as hydrochloride)
amodiaquine	Tablet	200 mg (as hydrochloride)
artemether	Oily injection	80 mg/ml in 1-ml ampoule
artemether + lumefantrine	Tablet	20 mg + 120 mg
artemether + lumefantrine	Tablet (dispersible)	20 mg + 120 mg	c2
artesunate	Injection	ampoules, containing 60 mg anhydrous artesunic acid with a separate ampoule of 5% sodium bicarbonate solution
artesunate	Rectal dosage form	100 mg	c1
artesunate	Rectal dosage form	200 mg capsules	c2
artesunate	Rectal dosage form	50 mg capsules	c2
artesunate	Tablet	50 mg
artesunate + amodiaquine	Tablet	100 mg + 270 mg
artesunate + amodiaquine	Tablet	25 mg + 67.5 mg
artesunate + amodiaquine	Tablet	50 mg + 135 mg
artesunate + mefloquine	Tablet	100 mg + 220 mg
artesunate + mefloquine	Tablet	25mg; 55mg
artesunate + pyronaride tetraphosphate	Granules	20 mg + 60 mg	a c1
artesunate + pyronaride tetraphosphate	Tablet	60 mg + 180 mg	a
chloroquine	Oral liquid	50 mg (as phosphate or sulfate)/5 ml
chloroquine	Tablet	100 mg (as phosphate or sulfate)
chloroquine	Tablet	150 mg (as phosphate or sulfate)
dihydroartemisinin + piperaquine phosphate	Tablet	20 mg + 160 mg	a
dihydroartemisinin + piperaquine phosphate	Tablet	40 mg + 320 mg	a
doxycycline	Capsule	100 mg (as hydrochloride or hyclate)
doxycycline	Tablet (dispersible)	100 mg (as monohydrate)
mefloquine	Tablet	250 mg (hydrochloride)
primaquine	Tablet	15 mg (as diphosphate)
primaquine	Tablet	7.5 mg (as diphosphate)
quinine	Injection	300 mg quinine hydrochloride/mL in 2-mL ampoule
quinine	Tablet	300 mg (quinine bisulfate)
quinine	Tablet	300 mg (quinine sulfate)
sulfadoxine + pyrimethamine	Tablet	500 mg + 25 mg

Medicine	Pharmaceutical form type	Composition	Observation
amodiaquine - sulfadoxine + pyrimethamine	Tablet (dispersible)	amodiaquine 153 mg (as hydrochloride) [3] and sulfadoxine + pyrimethamine 500 mg + 25 mg [1]	c1
amodiaquine - sulfadoxine + pyrimethamine	Tablet (dispersible)	amodiaquine 76.5 mg (as hydrochloride) [3] and sulfadoxine + pyrimethamine 250 mg + 12.5 mg [1]	c1
chloroquine	Oral liquid	50 mg (as phosphate or sulfate)/5 ml
chloroquine	Tablet	150 mg (as phosphate or sulfate)
doxycycline	Solid oral dosage form	100 mg (as hydrochloride or hyclate)	a
mefloquine	Tablet	250 mg (hydrochloride)	a
proguanil	Tablet	100 mg (as hydrochloride)

Medicine	Pharmaceutical form type	Composition	Observation
pyrimethamine	Tablet	25 mg
sulfadiazine	Tablet	500 mg
sulfamethoxazole + trimethoprim	Injection	80 mg + 16 mg/mL in 10-mL ampoule
sulfamethoxazole + trimethoprim	Injection	80 mg + 16 mg/mL in 5-mL ampoule
sulfamethoxazole + trimethoprim	Oral liquid	200 mg + 40 mg/5 mL
sulfamethoxazole + trimethoprim	Tablet	100 mg + 20 mg
sulfamethoxazole + trimethoprim	Tablet	400 mg + 80 mg	c2
sulfamethoxazole + trimethoprim	Tablet	800 mg + 160 mg

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
pentamidine	Tablet	200 mg (as isethionate)
pentamidine	Tablet	300 mg (as isethionate)

Medicine	Pharmaceutical form type	Composition	Observation
pentamidine	Injection	200 mg
suramin sodium	Powder for injection	1 g in vial

Medicine	Pharmaceutical form type	Composition
eflornithine	Injection	200 mg (hydrochloride)/ml in 100-ml bottle
melarsoprol	Injection	3.6% solution, 5-ml ampoule (180 mg of active compound)
nifurtimox	Tablet	120 mg

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
melarsoprol	Injection	3.6% solution, 5-ml ampoule (180 mg of active compound)	c1

Medicine	Pharmaceutical form type	Composition	Observation
benznidazole	Tablet	100 mg
benznidazole	Tablet	12,5 mg	c1
benznidazole	Tablet (scored)	50 mg
nifurtimox	Tablet	120 mg
nifurtimox	Tablet	250 mg
nifurtimox	Tablet	30 mg

Medicine	Pharmaceutical form type	Composition	Observation
ivermectin	Tablet (scored)	3 mg

07. ANTIMIGRAINE MEDICINES

Medicine	Pharmaceutical form type	Composition	Observation
acetylsalicylic acid	Tablet	300 mg to 500 mg
acetylsalicylic acid	Tablet	325 mg
acetylsalicylic acid	Tablet	500 mg
ibuprofen	Tablet	200 mg	c2
ibuprofen	Tablet	400 mg	c2
paracetamol	Oral liquid	120 mg/5 mL	c1
paracetamol	Oral liquid	125 mg/5 ml	c2
paracetamol	Tablet	300 mg to 500 mg
paracetamol	Tablet	325 mg
paracetamol	Tablet	500 mg
sumatriptan	Tablet	50 mg

Medicine	Pharmaceutical form type	Composition	Observation
propranolol	Tablet	20 mg (hydrochloride)	e
propranolol	Tablet	40 mg (hydrochloride)	e

08. IMMUNOMODULATORS AND ANTINEOPLASTICS

Medicine	Pharmaceutical form type	Composition	Observation
tacrolimus	Capsule	5 mg

Complementary list

Medicine	Pharmaceutical form type	Composition
adalimumab	Injection	40 mg/0.4 mL
adalimumab	Injection	40 mg/0.8 mL;
azathioprine	Powder for injection	100 mg (as sodium salt) in vial
azathioprine	Tablet	50 mg
ciclosporin	Capsule	25 mg
ciclosporin	Concentrate for injection	50 mg/ml in 1-ml ampoule
tacrolimus	Capsule	0.5 mg
tacrolimus	Capsule	0.75 mg
tacrolimus	Capsule	1 mg
tacrolimus	Capsule	2 mg
tacrolimus	Granules for oral suspension	0.2 mg
tacrolimus	Granules for oral suspension	1 mg
tacrolimus	Injection	5 mg/mL

Medicine	Pharmaceutical form type	Composition	Observation

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
arsenic trioxide	Concentrate for injection	1 mg/ ml
asparaginase	Powder for injection	10 000 IU in vial
bendamustine	Injection	180 mg/2 mL
bendamustine	Injection	45 mg/0.5 mL
bleomycin	Powder for injection	15 mg (as sulfate) in vial
calcium folinate	Injection	3 mg/mL in 10-mL ampoule
calcium folinate	Tablet	15 mg
calcium folinate	Tablet	25 mg
calcium folinate	Tablet	5 mg
capecitabine	Tablet	150 mg
capecitabine	Tablet	500 mg
carboplatin	Injection	150 mg/15 mL	e
carboplatin	Injection	450 mg/45 mL	e
carboplatin	Injection	50 mg/5 mL	e
carboplatin	Injection	600 mg/60 mL	e
chlorambucil	Tablet	2 mg
cisplatin	Injection	10 mg/10 ml
cisplatin	Injection	100 mg/100 mL
cisplatin	Injection	20 mg/20 mL
cisplatin	Injection	50 mg/ 50 ml
cyclophosphamide	Powder for injection	1 g in vial
cyclophosphamide	Powder for injection	2 g in vial
cyclophosphamide	Powder for injection	500 mg in vial
cyclophosphamide	Tablet	25 mg
cyclophosphamide	Tablet	50 mg
cytarabine	Powder for injection	100 mg in vial
dacarbazine	Powder for injection	100 mg in vial
dactinomycin	Powder for injection	500 mcg in vial
daunorubicin	Powder for injection	50 mg (hydrochloride) in vial
docetaxel	Injection	20 mg/ml
docetaxel	Injection	40 mg/mL
doxorubicin	Powder for injection	10 mg (hydrochloride) in vial
doxorubicin	Powder for injection	50 mg (hydrochloride) in vial
etoposide	Capsule	100 mg
etoposide	Capsule	50 mg
etoposide	Injection	20 mg/mL in 5-mL ampoule
fludarabine	Injection	50 mg (phosphate)
fludarabine	Tablet	10 mg
fluorouracil	Injection	50 mg/ml in 5-ml ampoule
gemcitabine	Injection	1 g
gemcitabine	Injection	200 mg
hydroxycarbamide	Solid oral dosage form	1 g
hydroxycarbamide	Solid oral dosage form	200 mg
hydroxycarbamide	Solid oral dosage form	250 mg
hydroxycarbamide	Solid oral dosage form	300 mg
hydroxycarbamide	Solid oral dosage form	400 mg
hydroxycarbamide	Solid oral dosage form	500 mg
ifosfamide	Powder for injection	1 g in vial
ifosfamide	Powder for injection	2 g in vial
ifosfamide	Powder for injection	500 mg vial
irinotecan	Injection	100 mg/ 5 ml in 5 ml vial
irinotecan	Injection	40 mg/ 2 ml in 2 ml vial
irinotecan	Injection	500 mg/ 25 ml in 25 ml vial
melphalan	Powder for injection	50mg.
melphalan	Tablet	2 mg
mercaptopurine	Tablet	50 mg
methotrexate	Powder for injection	50 mg (as sodium salt) in vial
methotrexate	Tablet	2.5 mg (as sodium salt)
oxaliplatin	Injection	100 mg/ 20 ml in 20 ml vial
oxaliplatin	Injection	200 mg/ 40 ml in 40 ml vial
oxaliplatin	Injection	50 mg/ 10 ml in 10 ml vial
oxaliplatin	Powder for injection	100 mg in vial
oxaliplatin	Powder for injection	50 mg in vial
paclitaxel	Powder for injection	6 mg/ml
pegaspargase	Injection	3.750 units/ 5 ml in vial
procarbazine	Capsule	50 mg (as hydrochloride)
realgar - indigo naturalis formulation	Tablet	270 mg
thioguanine	Solid oral dosage form	40 mg	c1
vinblastine	Powder for injection	10 mg (sulfate) in vial
vincristine	Injection	1 mg/mL
vincristine	Injection	2 mg/2 mL (sulfate) in vial
vincristine	Powder for injection	1 mg (sulfate) in vial
vincristine	Powder for injection	5 mg (sulfate) in vial
vinorelbine	Capsule	20 mg
vinorelbine	Capsule	30 mg
vinorelbine	Capsule	80 mg
vinorelbine	Injection	10 mg/mL
vinorelbine	Injection	50 mg

Medicine	Pharmaceutical form type	Composition	Observation

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
all trans retinoid acid (ATRA)	Capsule	10 mg
bortezomib	Powder for injection	3.5 mg in vial
dasatinib	Tablet	100 mg
dasatinib	Tablet	140 mg
dasatinib	Tablet	20 mg
dasatinib	Tablet	50 mg
dasatinib	Tablet	70 mg
dasatinib	Tablet	80 mg
erlotinib	Tablet	100 mg	e
erlotinib	Tablet	150 mg	e
everolimus	Tablet	10 mg
everolimus	Tablet	2.5 mg
everolimus	Tablet	5 mg
everolimus	Tablet	7.5 mg
everolimus	Tablet (dispersible)	2 mg
everolimus	Tablet (dispersible)	3 mg
everolimus	Tablet (dispersible)	5 mg
ibrutinib	Capsule	140 mg
imatinib	Tablet	100 mg (as mesylate)
imatinib	Tablet	400 mg (as mesylate)
nilotinib	Capsule	150 mg
nilotinib	Capsule	200 mg
rituximab	injection for intravenous administration	100 mg/ 10 ml in 10 ml vial
rituximab	injection for intravenous administration	500 mg/ 50 ml in 50 ml vial
trastuzumab	Powder for injection	150 mg
trastuzumab	Powder for injection	440 mg in vial
trastuzumab	Powder for injection	60 mg

Medicine	Pharmaceutical form type	Composition	Observation

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
filgrastim	Injection	120 micrograms/0.2 mL in pre-filled syringe.
filgrastim	Injection	300 micrograms/0.5 mL in pre-filled syringe.
filgrastim	Injection	300 micrograms/mL in 1 mL vial
filgrastim	Injection	480 micrograms/0.8 mL in pre-filled syringe
filgrastim	Injection	480 micrograms/1.6 mL in 1.6 mL vial
lenalidomide	Capsule	25 mg
nivolumab	Concentrate for solution for infusion	10 mg/ ml	e
thalidomide	Capsule	50 mg

Medicine	Pharmaceutical form type	Composition	Observation

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
abiraterone	Tablet	250 mg
abiraterone	Tablet	500 mg
anastrozole	Tablet	1mg
bicalutamide	Tablet	50 mg
dexamethasone	Injection	4 mg/mL in 1-mL ampoule (as disodium phosphate salt)
dexamethasone	Oral liquid	2 mg/5 mL	c1
dexamethasone	Tablet	2 mg	c1
dexamethasone	Tablet	4 mg
hydrocortisone	Powder for injection	100 mg (as sodium succinate) in vial
leuprorelin	Injection	22.5 mg in pre filled syringe
leuprorelin	Injection	7.5mg (acetate)
methylprednisolone	Injection	40 mg/mL (as sodium succinate) in 1-mL single dose vial	c1 c2
methylprednisolone	Injection	40 mg/mL (as sodium succinate) in 5-mL multidose vials	c2
methylprednisolone	Injection	80 mg/mL (as sodium succinate) in 1-mL single dose vial	c1
prednisolone	Oral liquid	5 mg/mL	c1 e
prednisolone	Tablet	25 mg	e
prednisolone	Tablet	5 mg	e
tamoxifen	Tablet	10 mg (as citrate)
tamoxifen	Tablet	20 mg (as citrate)

Medicine	Pharmaceutical form type	Composition	Observation

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
allopurinol	Tablet	100 mg	c1
allopurinol	Tablet	300 mg	c1
mesna	Injection	100 mg/ml in 10-ml ampoules
mesna	Injection	100 mg/ml in 4-ml ampoules
mesna	Tablet	400 mg
mesna	Tablet	600 mg
rasburicase	Powder and solvent for solution for infusion	1.5 mg in vial
rasburicase	Powder and solvent for solution for infusion	7.5 mg in vial
zoledronic acid	Concentrate for solution for infusion	4 mg/ 5 ml in 5 ml vial
zoledronic acid	Solution for IV infusion	4 mg/ 100 ml in 100 ml bottle

09. ANTIPARKINSONISM MEDICINES

Medicine	Pharmaceutical form type	Composition	Observation
biperiden	Injection	5 mg (lactate) in 1-ml ampoule	e
biperiden	Tablet	2 mg (hydrochloride)	e
levodopa + carbidopa	Tablet	100 mg + 10 mg	e
levodopa + carbidopa	Tablet	100 mg/ 25 mg	e
levodopa + carbidopa	Tablet	250 mg + 25 mg	e

10. MEDICINES AFFECTING THE BLOOD

Medicine	Pharmaceutical form type	Composition
ferrous salt	Oral liquid	equivalent to 25 mg iron (as sulfate)/ml
ferrous salt	Tablet	equivalent to 60 mg iron
ferrous salt + folic acid	Tablet	equivalent to 60 mg iron + 400 micrograms folic acid
folic acid	Tablet	0.4 mg
folic acid	Tablet	1 mg
folic acid	Tablet	5 mg
hydroxocobalamin	Injection	1 mg (as acetate, hydrochloride or as sulfate) in 1-ml ampoule

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
erythropoiesis - stimulating agents	injection: pre- filled syringe	10 000 IU/ 1 mL	e
erythropoiesis - stimulating agents	injection: pre- filled syringe	1000 IU/ 0.5 mL	e
erythropoiesis - stimulating agents	injection: pre- filled syringe	20 000 IU/ 0.5 mL	e
erythropoiesis - stimulating agents	injection: pre- filled syringe	2000 IU/ 0.5 mL	e
erythropoiesis - stimulating agents	injection: pre- filled syringe	3000 IU/ 0.3 mL	e
erythropoiesis - stimulating agents	injection: pre- filled syringe	40 000 IU/ 1 mL	e
erythropoiesis - stimulating agents	injection: pre- filled syringe	4000 IU/ 0.4 mL	e
erythropoiesis - stimulating agents	injection: pre- filled syringe	5000 IU/ 0.5 mL	e
erythropoiesis - stimulating agents	injection: pre- filled syringe	6000 IU/ 0.6 mL	e
erythropoiesis - stimulating agents	injection: pre- filled syringe	8000 IU/ 0.8 mL	e

Medicine	Pharmaceutical form type	Composition	Observation
dabigatran	Capsule	110 mg	e
dabigatran	Capsule	150 mg	e
enoxaparin	Injection	100 mg/ 1 mL
enoxaparin	Injection	120 mg/ 0.8 mL
enoxaparin	Injection	150 mg/ 1 mL
enoxaparin	Injection	20 mg/ 0.2 mL
enoxaparin	Injection	40 mg/ 0.4 mL
enoxaparin	Injection	60 mg/ 0.6 mL
enoxaparin	Injection	80 mg/ 0.8 mL
heparin sodium	Injection	1000 IU/mL in 1-mL ampoule
heparin sodium	Injection	20 000 IU/mL in 1-mL ampoule
heparin sodium	Injection	5000 IU/mL in 1-mL ampoule
phytomenadione	Injection	1 mg/mL in 5-mL ampoule	c2
phytomenadione	Injection	10 mg/mL in 5-mL ampoule
phytomenadione	Tablet	10 mg
protamine sulfate	Injection	10 mg/mL in 5-mL ampoule
tranexamic acid	Injection	100 mg/ml in 10-ml ampoule
warfarin	Tablet	1 mg (sodium salt)	e
warfarin	Tablet	2 mg (sodium salt)	e
warfarin	Tablet	5 mg (sodium salt)	e

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
desmopressin	Injection	4 mcg (acetate)/mL in 1 ml ampoule	c1
desmopressin	Nasal spray	0.1 mg (acetate)/mL	c1
heparin sodium	Injection	1000 IU/mL in 1-mL ampoule	c1
heparin sodium	Injection	5000 IU/mL in 1-mL ampoule	c1
protamine sulfate	Injection	10 mg/mL in 5-mL ampoule	c1
warfarin	Tablet	0.5 mg (sodium salt)	c1 e
warfarin	Tablet	1 mg (sodium salt)	c1 e
warfarin	Tablet	2 mg (sodium salt)	c1 e
warfarin	Tablet	5 mg (sodium salt)	c1 e

Medicine	Pharmaceutical form type	Composition	Observation

Complementary list

Medicine	Pharmaceutical form type	Composition
deferoxamine	Powder for injection	500 mg (mesilate) in vial
hydroxycarbamide	Solid oral dosage form	1 g
hydroxycarbamide	Solid oral dosage form	200 mg
hydroxycarbamide	Solid oral dosage form	500 mg

11.BLOOD PRODUCTS OF HUMAN ORIGIN AND PLASMA SUBSTITUTES

In accordance with the World Health Assembly resolution WHA63.12, WHO recognizes that achieving self-sufficiency, unless special circumstances preclude it, in the supply of safe blood components based on voluntary, non-remunerated blood donation, and the security of that supply are important national goals to prevent blood shortages and meet the transfusion requirements of the patient population. All preparations should comply with the WHO requirements.

Medicine	Pharmaceutical form type	Composition
fresh - frozen plasma	N/A	N/A
platelets	N/A	N/A
red blood cells	N/A	N/A
whole blood	N/A	N/A

Medicine	Pharmaceutical form type	Composition
anti-D immunoglobulin (human)	Injection	250 mcg in single-dose vial
antitetanus immunoglobulin (human)	Injection	500 IU in vial
rabies immunoglobulin	Injection	150 IU/mL in vial

Complementary list

Medicine	Pharmaceutical form type	Composition
human normal immunoglobulin	Intramuscular administration	16% protein solution
human normal immunoglobulin	Intravenous administration	10% protein solution
human normal immunoglobulin	Intravenous administration	5% protein solution
human normal immunoglobulin	Subcutaneous administration	15% protein solution
human normal immunoglobulin	Subcutaneous administration	16% protein solution

Medicine	Pharmaceutical form type	Composition	Observation

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
factor IX	Dried	1000 UI	e
factor IX	Dried	500 IU	e
factor VIII	Dried	500 UI	e

Medicine	Pharmaceutical form type	Composition	Observation
dextran 70	Intravenous administration	6% in 400 mL bottle	e

Medicine	Pharmaceutical form type	Composition
acetylsalicylic acid	Tablet	100 mg
clopidogrel	Tablet	300 mg
clopidogrel	Tablet	75 mg

12. CARDIOVASCULAR MEDICINES

Medicine	Pharmaceutical form type	Composition	Observation
bisoprolol	Tablet	1.25 mg	e
bisoprolol	Tablet	5 mg	e
glyceryl trinitrate	Tablet (sublingual)	500 mcg
isosorbide dinitrate	Tablet (sublingual)	5 mg	e
verapamil	Tablet	40 mg (hydrochloride)
verapamil	Tablet	80 mg (hydrochloride)

Medicine	Pharmaceutical form type	Composition	Observation
bisoprolol	Tablet	1.25 mg	e
bisoprolol	Tablet	5 mg	e
digoxin	Injection	250 micrograms/mL in 2-mL ampoule
digoxin	Oral liquid	50 micrograms/mL
digoxin	Tablet	250 mcg
digoxin	Tablet	62.5 micrograms
epinephrine (adrenaline)	Injection	100 micrograms/mL (as acid tartrate or hydrochloride) in 10-ml ampoule
lidocaine	Injection	20 mg (hydrochloride)/ml in 5-ml ampoule
verapamil	Injection	2.5 mg (hydrochloride)/mL in 2-mL ampoule
verapamil	Tablet	40 mg (hydrochloride)
verapamil	Tablet	80 mg (hydrochloride)

Complementary list

Medicine	Pharmaceutical form type	Composition
amiodarone	Injection	50 mg/mL in 3-mL ampoule (hydrochloride)
amiodarone	Tablet (HCI)	100 mg (hydrochloride)
amiodarone	Tablet (HCI)	200 mg (hydrochloride)
amiodarone	Tablet (HCI)	400 mg (hydrochloride)

Medicine	Pharmaceutical form type	Composition	Observation
amlodipine	Tablet	5 mg (as maleate, mesylate or besylate)	e
bisoprolol	Tablet	1.25 mg	e
bisoprolol	Tablet	5 mg	e
enalapril	Tablet	2.5 mg (as hydrogen maleate)	e
enalapril	Tablet	5 mg (as hydrogen maleate)	e
hydralazine	Powder for injection	20 mg (hydrochloride) in ampoule
hydralazine	Tablet	25 mg (hydrochloride)
hydralazine	Tablet	50 mg (hydrochloride)
hydrochlorothiazide	Oral liquid	50 mg/5 ml	e
hydrochlorothiazide	Solid oral dosage form	12.5 mg	e
hydrochlorothiazide	Solid oral dosage form	25 mg	e
lisinopril + amlodipine	Tablet	10 mg + 5 mg	e
lisinopril + amlodipine	Tablet	20 mg + 10 mg	e
lisinopril + amlodipine	Tablet	20 mg + 5 mg	e
lisinopril + hydrochlorothiazide	Tablet	10 mg + 12.5 mg	e
lisinopril + hydrochlorothiazide	Tablet	20 mg + 12.5 mg
lisinopril + hydrochlorothiazide	Tablet	20 mg + 25 mg	e
losartan	Tablet	100 mg
losartan	Tablet	25 mg	e
losartan	Tablet	50 mg	e
methyldopa	Tablet	250 mg
telmisartan + amlodipine	Tablet	40 mg + 5 mg	e
telmisartan + amlodipine	Tablet	80 mg + 10 mg
telmisartan + amlodipine	Tablet	80 mg + 5 mg	e
telmisartan + hidroclorotiazida	Tablet	40 mg + 12.5 mg	e
telmisartan + hidroclorotiazida	Tablet	80 mg + 25 mg	e
telmisartan + hidroclorotiazida	Tablet	80 mg/ 12.5 mg	e

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
sodium nitroprusside	Powder for infusion	50 mg in ampoule

Medicine	Pharmaceutical form type	Composition	Observation
bisoprolol	Tablet	1.25 mg	e
bisoprolol	Tablet	5 mg	e
digoxin	Injection	250 micrograms/mL in 2-mL ampoule
digoxin	Oral liquid	50 micrograms/mL
digoxin	Tablet	250 mcg
digoxin	Tablet	62.5 micrograms
enalapril	Tablet	2.5 mg (as hydrogen maleate)	e
enalapril	Tablet	5 mg (as hydrogen maleate)	e
furosemide	Injection	10 mg/mL in 2-mL ampoule	e
furosemide	Oral liquid	20 mg/5 mL	c2 e
furosemide	Tablet	40 mg	e
hydrochlorothiazide	Oral liquid	50 mg/5 ml	e
hydrochlorothiazide	Solid oral dosage form	25 mg	e
losartan	Tablet	100 mg	e
losartan	Tablet	25 mg	e
losartan	Tablet	50mg	e
spironolactone	Tablet	25 mg

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
dopamine	Injection	40 mg/mL (hydrochloride) in 5-mL vial

Medicine	Pharmaceutical form type	Composition
acetylsalicylic acid	Tablet	100 mg
clopidogrel	Tablet	300 mg
clopidogrel	Tablet	75 mg

Medicine	Pharmaceutical form type	Composition	Observation

Complementary list

Medicine	Pharmaceutical form type	Composition
alteplase	Injection	50 mg
alteplase	Powder for injection	10 mg
alteplase	Powder for injection	20 mg
streptokinase	Powder for injection	1.5 million IU in vial

Medicine	Pharmaceutical form type	Composition	Observation
simvastatin	Tablet	10 mg	e
simvastatin	Tablet	20 mg	e
simvastatin	Tablet	40 mg	e
simvastatin	Tablet	5 mg	e

13. DERMATOLOGICAL MEDICINES (topical)

Medicine	Pharmaceutical form type	Composition	Observation
miconazole	Cream	2% (nitrate)	e
miconazole	Ointment	2% (nitrate)	e
selenium sulfide	Detergent-based suspension	2%
sodium thiosulfate	Solution	15%
terbinafine	Cream	1%
terbinafine	Ointment	1% terbinafine hydrochloride

Medicine	Pharmaceutical form type	Composition	Observation
mupirocin	Cream	2 % (as mupirocin calcium)
mupirocin	Ointment	2%
potassium permanganate	Aqueous solution	1:10 000
silver sulfadiazine	Cream	1%	a

Medicine	Pharmaceutical form type	Composition	Observation
betamethasone	Cream	0.1% (as valerate)	a e
betamethasone	Ointment	0.1% (as valerate)	a e
calamine	Lotion	N/A	e
hydrocortisone	Cream	1% (acetate)	e
hydrocortisone	Ointment	1% (acetate)	e

Medicine	Pharmaceutical form type	Composition	Observation
benzoyl peroxide	Cream	5%
benzoyl peroxide	Lotion	5%
calcipotriol	Cream	50 micrograms/mL (0.005%)
calcipotriol	Lotion	50 micrograms/mL (0.005%)
calcipotriol	Ointment	50 micrograms/mL (0.005%)
coal tar	Solution	5%
fluorouracil	Ointment	5%
podophyllum resin	Solution	10% to 25%	e
salicylic acid	Solution	5%
urea	Cream	10%
urea	Cream	5%
urea	Ointment	10%
urea	Ointment	5%

Medicine	Pharmaceutical form type	Composition	Observation
benzyl benzoate	Lotion	25%	a e
permethrin	Cream	5%
permethrin	Lotion	1%

14. DIAGNOSTIC AGENTS

Medicine	Pharmaceutical form type	Composition	Observation
fluorescein	Solution (eye drops)	1% (sodium salt)
tropicamide	Solution (eye drops)	0.5%	e

Medicine	Pharmaceutical form type	Composition	Observation
amidotrizoate	Injection	140 mg to 420 mg iodine (as sodium or meglumine salt)/ml in 20-ml ampoule	e
barium sulfate	Aqueous suspension	N/A	c1
iohexol	Injection	140 mg to 350 mg iodine/ml in 10-ml ampoules	e
iohexol	Injection	140 mg to 350 mg iodine/ml in 20-ml ampoules	e
iohexol	Injection	140 mg to 350 mg iodine/ml in 5-ml ampoules	e

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
barium sulfate	Aqueous suspension	N/A
meglumine iotroxate	Solution	5 g to 8 g iodine in 100 ml to 250 ml	e

15. ANTISEPTICS AND DISINFECTANTS

Medicine	Pharmaceutical form type	Composition	Observation
chlorhexidine	Solution	5% (digluconate)	e
ethanol	Solution	70% (denatured)	e
polyvidone iodine	Solution	10%	e

Medicine	Pharmaceutical form type	Composition	Observation
alcohol based hand rub	Solution	containing ethanol 80% volume/volume
alcohol based hand rub	Solution	containing isopropyl alcohol 75% volume/volume
chlorine base compound	Liquid	(0.1% available chlorine) for solution
chlorine base compound	Powder	(0.1% available chlorine) for solution	e
chlorine base compound	Solid	0.1% available chlorine) for solution
chloroxylenol	Solution	4.8%	e
glutaral	Solution	2%

16. DIURETICS

Medicine	Pharmaceutical form type	Composition	Observation
amiloride	Tablet	5 mg (hydrochloride)
furosemide	Injection	10 mg/mL in 2-mL ampoule	e
furosemide	Oral liquid	20 mg/5 mL	c2 e
furosemide	Tablet	10 mg	c2 e
furosemide	Tablet	20 mg	c2 e
furosemide	Tablet	40 mg	e
hydrochlorothiazide	Solid oral dosage form	25 mg	e
mannitol	Injectable solution	10%
mannitol	Injectable solution	20%
spironolactone	Tablet	25 mg

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
hydrochlorothiazide	Tablet (scored)	25 mg	c1 e
mannitol	Injectable solution	10%	c1
mannitol	Injectable solution	20%	c1
spironolactone	Oral liquid	10 mg/5 ml	c1
spironolactone	Oral liquid	25 mg/5 ml	c1
spironolactone	Oral liquid	5 mg/5 ml	c1
spironolactone	Tablet	25 mg	c1

17. GASTROINTESTINAL MEDICINES

Medicine	Pharmaceutical form type	Composition	Observation
omeprazole	Powder for injection	40 mg in vial	e
omeprazole	Powder for oral liquid	20 mg sachets	e
omeprazole	Powder for oral liquid	40 mg sachets	e
omeprazole	Solid oral dosage form	10 mg	e
omeprazole	Solid oral dosage form	20 mg	e
omeprazole	Solid oral dosage form	40 mg
ranitidine	Injection	25 mg/mL (as hydrochloride) in 2-mL ampoule	e
ranitidine	Oral liquid	75 mg/5 mL (as hydrochloride)	e
ranitidine	Tablet	150 mg (as hydrochloride)	e

Medicine	Pharmaceutical form type	Composition	Observation
dexamethasone	Injection	4 mg/mL in 1-mL ampoule (as disodium phosphate salt)
dexamethasone	Oral liquid	0.5 mg/5 mL
dexamethasone	Oral liquid	2 mg/5 mL
dexamethasone	Solid oral dosage form	0.5 mg
dexamethasone	Solid oral dosage form	0.75 mg
dexamethasone	Solid oral dosage form	1.5 mg
dexamethasone	Solid oral dosage form	4 mg
metoclopramide	Injection	5 mg (hydrochloride)/mL in 2-mL ampoule	a
metoclopramide	Oral liquid	5 mg/5 mL	a c2
metoclopramide	Tablet	10 mg (hydrochloride)	a
ondansetron	Injection	2 mg base/ml in 2-ml ampoule (as hydrochloride)	a
ondansetron	Oral liquid	4 mg base/5 ml	a
ondansetron	Solid oral dosage form	Eq 24 mg base	a
ondansetron	Solid oral dosage form	Eq 4 mg base	a
ondansetron	Solid oral dosage form	Eq 8 mg base	a

Complementary list

Medicine	Pharmaceutical form type	Composition
aprepitant	Capsule	125 mg
aprepitant	Capsule	165 mg
aprepitant	Capsule	80 mg
aprepitant	Powder for oral suspension	125 mg in sachet

Medicine	Pharmaceutical form type	Composition	Observation
sulfasalazine	Retention enema	N/A	e
sulfasalazine	Suppository	500 mg	e
sulfasalazine	Tablet	500 mg	e

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
hydrocortisone	Retention enema	N/A	e
hydrocortisone	Suppository	25 mg (acetate)
prednisolone	Retention enema	20 mg/100 mL (as sodium phosphate)

Medicine	Pharmaceutical form type	Composition	Observation
senna	Tablet	7.5 mg (sennosides)	e

Medicine	Pharmaceutical form type	Composition
oral rehydration salts	Powder for dilution	1 L
oral rehydration salts	Powder for dilution	200 ml
oral rehydration salts	Powder for dilution	500 ml

Medicine	Pharmaceutical form type	Composition	Observation
zinc sulfate	Solid oral dosage form	20 mg

18. MEDICINES FOR ENDOCRINE DISORDERS

Medicine	Pharmaceutical form type	Composition
fludrocortisone	Tablet	100 mcg (acetate)
hydrocortisone	Tablet	10 mg
hydrocortisone	Tablet	20 mg
hydrocortisone	Tablet	5 mg

Medicine	Pharmaceutical form type	Composition	Observation

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
testosterone	Injection	200 mg (enanthate) in 1-mL ampoule

Medicine	Pharmaceutical form type	Composition	Observation

Medicine	Pharmaceutical form type	Composition	Observation
medroxyprogesterone acetate	Tablet	5 mg	e

Medicine	Pharmaceutical form type	Composition
insulin injection (soluble)	Injection	40 IU/ml in 10-ml vial
intermediate-acting insulin	Injection	100 IU/ml in 10-ml vial
intermediate-acting insulin	Injection	40 IU/ml in 10-ml vial
long-acting insulin analogues	Injection	100 IU/mL in 3 mL cartridge or pre-filled pen

Medicine	Pharmaceutical form type	Composition	Observation
empagliflozina	Tablet	10 mg
empagliflozina	Tablet	25 mg
gliclazide	Solid oral dosage form	30 mg	e
gliclazide	Solid oral dosage form	60 mg	e
gliclazide	Solid oral dosage form	80 mg	e
metformin	Tablet	500 mg (hydrochloride)	c1
metformin	Tablet	500 mg (hydrochloride)

Medicine	Pharmaceutical form type	Composition	Observation
diazoxide	Oral liquid	50 mg/ ml	c1
diazoxide	Tablet	50 mg	c1
glucagon	Injection	1 mg/mL

Medicine	Pharmaceutical form type	Composition	Observation
levothyroxine	Tablet	100 mcg (sodium salt)
levothyroxine	Tablet	25 mcg (sodium salt)	c2
levothyroxine	Tablet	50 mcg (sodium salt)
methamizole	Tablet	10 mg	e
methimazole	Tablet	20 mg	e
methimazole	Tablet	5 mg	e
potassium iodide	Tablet	60 mg
propylthiouracil	Tablet	50 mg	e

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
Lugol's solution	Oral liquid	about 130 mg total iodine/ml	c1
methimazole	Tablet	10 mg	c1
methimazole	Tablet	20 mg	c1
methimazole	Tablet	5 mg	c1
potassium iodide	Tablet	60 mg	c1
propylthiouracil	Tablet	50 mg	c1

19. IMMUNOLOGICALS

All tuberculins should comply with the WHO Requirements for Tuberculins.

Medicine	Pharmaceutical form type	Composition	Observation
tuberculin, purified protein derivative (PPD)	Injection	N/A

All plasma fractions should comply with the WHO Requirements.

Medicine	Pharmaceutical form type	Composition
anti-rabies virus monoclonal antibodies	Injection	100 IU/mL in 2.5 mL vial (human)
anti-rabies virus monoclonal antibodies	Injection	300 IU/mL in 10 mL vial (murine)
anti-rabies virus monoclonal antibodies	Injection	40 IU/mL in 1.25 mL vial (human)
anti-rabies virus monoclonal antibodies	Injection	40 IU/mL in 2.5 mL vial (human)
anti-rabies virus monoclonal antibodies	Injection	600 IU/mL in 1 mL (murine)
anti-rabies virus monoclonal antibodies	Injection	600 IU/mL in 2.5 mL (murine)
anti-rabies virus monoclonal antibodies	Injection	600 IU/mL in 5 mL (murine)
antivenom immunoglobulin	Injection	N/A
diphtheria antitoxin	Injection	10 000 IU in vial
diphtheria antitoxin	Injection	20 000 IU in vial
rabies immunoglobulin	Injection	150 IU/ml in vial
rabies immunoglobulin	Injection	200 IU/mL in vial
rabies immunoglobulin	Injection	300 IU/mL in vial
rabies immunoglobulin	Injection	400 IU/mL in vial

WHO immunization policy recommendations are published in vaccine position papers based on recommendations made by the Strategic Advisory Group of Experts on Immunization (SAGE). WHO vaccine position papers are updated three to four times per year. The list below details the vaccines for which there is a recommendation from SAGE and a corresponding WHO position paper as at September 2020. The most recent versions of the WHO position papers, reflecting the current evidence related to a specific vaccine and the related recommendations, can be accessed at any time on the WHO website at: https://www.who.int/teams/immunization-vaccines-and-biologicals/policies/position-papers Vaccine recommendations may be universal or conditional (e.g., in certain regions, in some high-risk populations or as part of immunization programmes with certain characteristics). Details are available in the relevant position papers, and in the Summary Tables of WHO Routine Immunization Recommendations available on the WHO website at: https://www.who.int/teams/immunization-vaccines-and-biologicals/policies/who-recommendations-for-routine-immunization---summary-tables Selection of vaccines from the Model List will need to be determined by each country after consideration of international recommendations, epidemiology and national priorities. All vaccines should comply with the WHO requirements for biological substances. WHO noted the need for vaccines used in children to be polyvalent.

Medicine	Pharmaceutical form type	Composition
BCG vaccine	Injection	N/A
diphtheria vaccine	Injection	N/A
haemophilus influenzae type b vaccine (Hib vaccine)	N/A	N/A
hepatitis B vaccine	Injection	N/A
human papilloma virus (HPV) vaccine	N/A	N/A
measles vaccine	Injection	N/A
pertussis vaccine	N/A	N/A
pneumococcal vaccine	N/A	N/A
poliomyelitis vaccine	Powder	N/A
rotavirus vaccine	N/A	N/A
rubella vaccine	N/A	N/A
tetanus vaccine	Injection	N/A

Medicine	Pharmaceutical form type	Composition
japanese encephalitis vaccine	N/A	N/A
tick-borne encephalitis vaccine	N/A	N/A
yellow fever vaccine	N/A	N/A

Medicine	Pharmaceutical form type	Composition
influenza vaccine	N/A	N/A
mumps vaccine	N/A	N/A
varicella vaccine	N/A	N/A

Medicine	Pharmaceutical form type	Composition
cholera vaccine	N/A	N/A
dengue vaccine	N/A	N/A
hepatitis A vaccine	N/A	N/A
meningococcal meningitis vaccine	N/A	N/A
rabies vaccine	N/A	N/A
typhoid vaccine	N/A	N/A

20. MUSCLE RELAXANTS (PERIPHERALLY-ACTING) AND CHOLINESTERASE INHIBITORS

Medicine	Pharmaceutical form type	Composition	Observation
atracurium	Injection	10 mg/mL (besylate)	e
neostigmine	Injection	2.5 mg (metilsulfate) in 1-ml ampoule
neostigmine	Injection	500 mcg in 1-mL ampoule
neostigmine	Tablet	15 mg (bromide)
suxamethonium	Injection	50 mg (chloride)/ml in 2-ml ampoule
suxamethonium	Powder for injection	(chloride), in vial
vecuronium	Powder for injection	10 mg (bromide)/mL in ampoule	c2 e

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
pyridostigmine	Injection	1 mg in 1-mL ampoule
pyridostigmine	Tablet	60 mg (bromide)
vecuronium	Powder for injection	10 mg (bromide)/mL in ampoule	e

21. OPHTHALMOLOGICAL PREPARATIONS

Medicine	Pharmaceutical form type	Composition	Observation
aciclovir	Ointment	3% W/W
azithromycin	Solution (eye drops)	1.5%
erythromycin	Ointment	0.5%	c1
gentamicin	Solution (eye drops)	0.3% (sulfate)	e
natamycin	Suspension (eye drops)	5%
ofloxacin	Solution (eye drops)	0.3%	e
tetracycline	Eye ointment	1% (hydrochloride)	e

Medicine	Pharmaceutical form type	Composition	Observation
prednisolone	Solution (eye drops)	0.5% (sodium phosphate)	e

Medicine	Pharmaceutical form type	Composition	Observation
tetracaine	Solution (eye drops)	0.5% (hydrochloride)	a e

Medicine	Pharmaceutical form type	Composition	Observation
acetazolamide	Tablet	250 mg
latanoprost	Solution (eye drops)	0.005%
pilocarpine	Solution (eye drops)	2% (hydrochloride or nitrate)	e
pilocarpine	Solution (eye drops)	4% (hydrochloride or nitrate)	e
timolol	Solution (eye drops)	0.25% (maleate)	e
timolol	Solution (eye drops)	0.5% (maleate)	e

Medicine	Pharmaceutical form type	Composition	Observation
atropine	Solution (eye drops)	0.1% (sulfate)	a c2
atropine	Solution (eye drops)	0.5% (sulfate)	a c2
atropine	Solution (eye drops)	1% (sulfate)	a c2

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
epinephrine (adrenaline)	Solution (eye drops)	2% (as hydrochloride)

Medicine	Pharmaceutical form type	Composition	Observation
bevacizumab	Injection	25 mg/ml

22. MEDICINES FOR REPRODUCTIVE HEALTH AND PERINATAL CARE

Medicine	Pharmaceutical form type	Composition	Observation
ethinylestradiol + levonorgestrel	Tablet	30 mcg + 50 mcg	e
ethinylestradiol + norethisterone	Tablet	35 micrograms + 1 mg	e
levonorgestrel	Tablet	1.5 mg
levonorgestrel	Tablet	30 micrograms
levonorgestrel	Tablet	750 micrograms (pack of two)
ulipristal	Tablet	30 mg (as acetate)

Medicine	Pharmaceutical form type	Composition
estradiol cypionate + medroxyprogesterone acetate	Injection	5 mg + 25 mg
medroxyprogesterone acetate	Depot injection	150 mg/ ml in 1 ml vial
medroxyprogesterone acetate	injection (subcutaneous)	104 mg/0.65 mL in pre-filled syringe or single-dose injection delivery system
norethisterone enantate	Oily solution	200 mg/ml in 1-ml ampoule

Medicine	Pharmaceutical form type	Composition	Observation
copper-containing device	N/A	N/A
levonorgestrel-releasing intrauterine system	Intrauterine system	with reservoir containing 52 mg of levonogestrel

Medicine	Pharmaceutical form type	Composition	Observation
condoms	N/A	N/A
diaphragms	N/A	N/A

Medicine	Pharmaceutical form type	Composition	Observation
etonogestrel-releasing implant	N/A	Two-rod levonorgestrel-releasing implant: each rod containing 75 mg of levonorgestrel (150 mg total)
levonorgestrel-releasing implant	N/A	Two-rod levonorgestrel-releasing implant, each rod containing 75 mg of levonorgestrel (150 mg total)

Medicine	Pharmaceutical form type	Composition	Observation
ethinylestradiol + etonogestrel	Vaginal ring	containing 2.7 mg + 11.7 mg
progesterone	Vaginal ring	containing 2.074 g of micronized progesterone

Medicine	Pharmaceutical form type	Composition	Observation

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
clomifene	Tablet	50 mg (citrate)

Medicine	Pharmaceutical form type	Composition	Observation
carbetocin	Injection (heat stable)	100 mcg/ml
ergometrine	Injection	0.2 mg/mL (maleate) in 1-mL ampoule	e
mifepristone + misoprostol	N/A	Co-package containing: mifepristone 200 mg tablet [1] and misoprostol 200 micrograms tablet [4]
mifepristone + misoprostol	Tablet	200 mg + 200 micrograms
misoprostol	Tablet	200 mcg
misoprostol	Vaginal tablet	25 mcg
oxytocin	Injection	10 IU in 1-mL ampoule

Medicine	Pharmaceutical form type	Composition	Observation
nifedipine	Immediate-release capsule	10 mg

Medicine	Pharmaceutical form type	Composition
dexamethasone	Injection	4 mg/mL in 1-mL ampoule (as disodium phosphate salt)
multiple micronutrient powder	Tablet	See observations
tranexamic acid	Injection	100 mg/ml in 10-ml ampoule

Medicine	Pharmaceutical form type	Composition	Observation
caffeine citrate	Injection	20 mg/ml (equivalent to 10 mg caffeine base/ml)	c1
caffeine citrate	Oral liquid	20 mg/ml (equivalent to 10 mg caffeine base/ml)	c1
chlorhexidine	Gel	7.1% (digluconate) delivering 4% chlorhexidine (for umbilical cord care)
chlorhexidine	Solution	7.1% (digluconate) delivering 4% chlorhexidine (for umbilical cord care)	c1

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
ibuprofen	Solution for injection	5 mg/mL	c1 e
prostaglandin E	Solution for injection	Prostaglandin E1: 0.5 mg/ml in alcohol	c1 e
surfactant	Suspension for intratracheal instillation	25 mg/ml	c1
surfactant	Suspension for intratracheal instillation	80 mg/ml	c1

23. PERITONEAL DIALYSIS SOLUTION

Medicine	Pharmaceutical form type	Composition	Observation

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
intraperitoneal dialysis solution (of appropriate composition)	Parenteral solution	N/A

24. MEDICINES FOR MENTAL AND BEHAVIOURAL DISORDERS

Medicine	Pharmaceutical form type	Composition	Observation
chlorpromazine	Injection	25 mg (hydrochloride)/mL in 2-mL ampoule	e
chlorpromazine	Oral liquid	25 mg (hydrochloride)/5 mL	e
chlorpromazine	Tablet	100 mg (hydrochloride)	e
clozapine	Solid oral dosage form	25 to 200 mg
fluphenazine	Injection	25 mg (decanoate or enantate) in 1-mL ampoule	e
haloperidol	Injection	5 mg/mL in 1-mL ampoule	e
haloperidol	Tablet	2 mg	e
haloperidol	Tablet	5 mg	e
risperidone	Solid oral dosage form	0.25 mg to 6.0 mg

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
chlorpromazine	Injection	25 mg (hydrochloride)/mL in 2-mL ampoule	c1
chlorpromazine	Oral liquid	25 mg (hydrochloride)/5 mL	c1
chlorpromazine	Tablet	10 mg (hydrochloride)	c1
chlorpromazine	Tablet	100 mg (hydrochloride)	c1
chlorpromazine	Tablet	25 mg (hydrochloride)	c1
chlorpromazine	Tablet	50 mg (hydrochloride)	c1
haloperidol	Injection	5 mg/mL in 1-mL ampoule	c1
haloperidol	Oral liquid	2 mg/mL	c1
haloperidol	Solid oral dosage form	0.5 mg	c1
haloperidol	Solid oral dosage form	2 mg	c1
haloperidol	Solid oral dosage form	5 mg	c1

Medicine	Pharmaceutical form type	Composition	Observation
amitriptyline	Tablet	25 mg (hydrochloride)	e
amitriptyline	Tablet	75 mg (hydrochloride)
fluoxetine	Solid oral dosage form	20 mg (as hydrochloride)

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
fluoxetine	Solid oral dosage form	20 mg (as hydrochloride)	a c1

Medicine	Pharmaceutical form type	Composition
carbamazepine	Tablet (scored)	100 mg
carbamazepine	Tablet (scored)	200 mg
lithium carbonate	Solid oral dosage form	300 mg
valproic acid (sodium valproate)	Tablet (enteric-coated)	200 mg (sodium valproate)
valproic acid (sodium valproate)	Tablet (enteric-coated)	500 mg (sodium valproate)

Medicine	Pharmaceutical form type	Composition	Observation
diazepam	Tablet (scored)	2 mg	e
diazepam	Tablet (scored)	5 mg	e

Medicine	Pharmaceutical form type	Composition	Observation
clomipramine	Capsule	10 mg (hydrochloride)
clomipramine	Capsule	25 mg (hydrochloride)

Medicine	Pharmaceutical form type	Composition
nicotine replacement therapy (NRT)	Chewing gum	2 mg (as polacrilex)
nicotine replacement therapy (NRT)	Chewing gum	4 mg (as polacrilex)
nicotine replacement therapy (NRT)	Transdermal patches	5 mg to 30 mg/16 hrs
nicotine replacement therapy (NRT)	Transdermal patches	7 mg to 21 mg/24 hrs

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
methadone	Concentrate for oral liquid	10 mg/ml (hydrochloride)	e
methadone	Concentrate for oral liquid	5 mg/ml (hydrochloride)	e
methadone	Oral liquid	10 mg/5 ml (hydrochloride)	e
methadone	Oral liquid	5 mg/5 ml (hydrochloride)	e

25. MEDICINES ACTING ON THE RESPIRATORY TRACT

Medicine	Pharmaceutical form type	Composition	Observation
budesonide	Inhalation (aerosol)	100 micrograms per dose	c2 e
budesonide	Inhalation (aerosol)	200 micrograms per dose	c2 e
budesonide + formoterol	Powder for inhalacion	100 micrograms + 6 micrograms per dose
budesonide + formoterol	Powder for inhalacion	200 micrograms + 6 micrograms per dose
epinephrine (adrenaline)	Injection	1 mg (as hydrochloride or hydrogen tartrate) in 1-ml ampoule
ipratropium bromide	Inhalation (aerosol)	20 micrograms/metered dose
salbutamol	Inhalation (aerosol)	100 mcg (as sulfate) per dose	e
salbutamol	Injection	50 mcg (as sulfate)/mL in 5-mL ampoule	e
salbutamol	Metered dose inhaler (aerosol)	100 mcg (as sulfate) per dose	e
salbutamol	respirator solution for use in nebulizers	5 mg (as sulfate)/mL	e
tiotropium	Capsule	18 mcg
tiotropium	Powder for inhalacion	18 mcg
tiotropium	Solution for inhalation	1.25 mcg per actuation
tiotropium	Solution for inhalation	2.5 mcg per actuation

26. SOLUTIONS CORRECTING WATER, ELECTROLYTE AND ACID-BASE DISTURBANCES

Medicine	Pharmaceutical form type	Composition
oral rehydration salts	Powder for dilution	1 L
oral rehydration salts	Powder for dilution	200 ml
oral rehydration salts	Powder for dilution	500 ml
potassium chloride	Powder for solution	N/A

Medicine	Pharmaceutical form type	Composition	Observation
glucose	Injectable solution	10% (hypertonic)
glucose	Injectable solution	5% (isotonic)
glucose	Injectable solution	50% (hypertonic)
glucose with sodium chloride	Injectable solution	4% glucose, 0.18% sodium chloride (equivalent to Na+ 30 mmol/L, Cl- 30 mmol/L)
glucose with sodium chloride	Injectable solution	5% glucose, 0.9% sodium chloride (equivalent to 150 mmol/L Na+ and 150 mmol/L Cl-)	c2
potassium chloride	Solution	11.2% in 20-ml ampoule (equivalent to K+ 1.5 mmol/ml, Cl 1.5 mmol/ml)
potassium chloride	Solution for dilution	15% (equivalent to K 2 mmol/ml and Cl 2 mmol/ml)	c2
potassium chloride	Solution for dilution	7.5% (equivalent to K 1 mmol/ml and Cl 1 mmol/ml)	c2
sodium chloride	Injectable solution	0.9% isotonic (equivalent to Na+ 154 mmol/L, Cl- 154 mmol/L)
sodium hydrogen carbonate	Injectable solution	1.4% isotonic (equivalent to Na+ 167 mmol/L, HCO3- 167 mmol/L)
sodium hydrogen carbonate	Solution	8.4% in 10-ml ampoule (equivalent to Na+ 1000 mmol/L, HCO3-1000 mmol/L)
sodium lactate, compound	Injectable solution	N/A	e

Medicine	Pharmaceutical form type	Composition
water for injection	N/A	10-ml ampoules
water for injection	N/A	2-ml ampoules
water for injection	N/A	5-mL ampoules

27. VITAMINS AND MINERALS

Medicine	Pharmaceutical form type	Composition	Observation
ascorbic acid	Tablet	50 mg
calcium	Tablet	500 mg (elemental)
cholecalciferol	Oral liquid	400 IU/ml	c2
cholecalciferol	Solid oral dosage form	1000 IU	c2
cholecalciferol	Solid oral dosage form	400 IU	c2
ergocalciferol	Oral liquid	250 micrograms/ml (10 000 IU/ml)	e
ergocalciferol	Solid oral dosage form	1.25 mg (50 000 IU)	e
iodine	Capsule	200 mg
iodine	Iodized oil	0.5 ml (240 mg iodine) in ampoule (oral or injectable)
iodine	Iodized oil	0.57 ml (308 mg iodine) in dispenser bottle
iodine	Iodized oil	1 ml (480 mg iodine) in ampoule (oral or injectable)
multiple micronutrient powder	Sachet	iron (elemental) 12.5 mg (as coated ferrous fumarate) + zinc (elemental) 5 mg + vitamin A 300 micrograms-with or without other micronutrients at recommended daily values)	c1
nicotinamide	Tablet	50 mg	e
pyridoxine	Tablet	25 mg (hydrochloride)
retinol	Capsule	100 000 IU (as palmitate)
retinol	Capsule	200 000 IU (as palmitate)
retinol	Capsule	50 000 IU (as palmitate)
retinol	Oral oily solution	100 000 IU (as palmitate)/ml in multidose dispenser
retinol	Tablet (sugar-coated)	10 000 IU (as palmitate)
retinol	Water-miscible injection	100 000 IU (as palmitate) in 2-ml ampoule
riboflavin	Tablet	5 mg
thiamine	Tablet	50 mg (hydrochloride)

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
calcium gluconate	Injection	100 mg/mL in 10-mL ampoule

28. EAR, NOSE and THROAT MEDICINES

Medicine	Pharmaceutical form type	Composition	Observation
acetic acid	Topical	2%, in alcohol	c2
budesonide	Nasal spray	100 micrograms per dose	c2
ciprofloxacin	Topical	0.3% drops (as hydrochloride)	c2
xylometazoline	Nasal spray	0.05%	a c2

29. MEDICINES FOR DISEASES OF JOINTS

Medicine	Pharmaceutical form type	Composition	Observation
allopurinol	Tablet	100 mg

Medicine	Pharmaceutical form type	Composition
chloroquine	Tablet	100 mg (as phosphate or sulfate)
chloroquine	Tablet	150 mg (as phosphate or sulfate)
methotrexate	Tablet	2.5 mg (as sodium salt)
sulfasalazine	Tablet	500 mg

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
azathioprine	Tablet	50 mg
hydroxychloroquine	Solid oral dosage form	200 mg (as sulfate)	c1
penicillamine	Solid oral dosage form	250 mg

Medicine	Pharmaceutical form type	Composition	Observation

Complementary list

Medicine	Pharmaceutical form type	Composition
acetylsalicylic acid	Suppository	120 mg
acetylsalicylic acid	Suppository	50 mg to 150 mg
acetylsalicylic acid	Suppository	60 mg
acetylsalicylic acid	Tablet	100 mg to 500 mg
acetylsalicylic acid	Tablet	325 mg
acetylsalicylic acid	Tablet	500 mg

30. DENTAL PREPARATIONS

Medicine	Pharmaceutical form type	Composition
fluoride	Paste, cream or gel	containing between 1000 and 1500 ppm fluoride (any type)
glass ionomer cement	Multi-use bottle	powder + liquid
glass ionomer cement	Single-use capsules	0.4 g powder + 0.09 mL liquid
silver diamine fluoride	Solution	38% w/v

01. ANAESTHETICS, PREOPERATIVE MEDICINES AND MEDICAL GASES 02. MEDICINES FOR PAIN AND PALLIATIVE CARE 03. ANTIALLERGICS AND MEDICINES USED IN ANAPHYLAXIS 04. ANTIDOTES AND OTHER SUBSTANCES USED IN POISONINGS 05. ANTICONVULSANTS/ ANTIEPILEPTICS 06. ANTI-INFECTIVE MEDICINES 07. ANTIMIGRAINE MEDICINES 08. IMMUNOMODULATORS AND ANTINEOPLASTICS 09. ANTIPARKINSONISM MEDICINES 10. MEDICINES AFFECTING THE BLOOD 11.BLOOD PRODUCTS OF HUMAN ORIGIN AND PLASMA SUBSTITUTES 12. CARDIOVASCULAR MEDICINES 13. DERMATOLOGICAL MEDICINES (topical) 14. DIAGNOSTIC AGENTS 15. ANTISEPTICS AND DISINFECTANTS 16. DIURETICS 17. GASTROINTESTINAL MEDICINES 18. MEDICINES FOR ENDOCRINE DISORDERS 19. IMMUNOLOGICALS 20. MUSCLE RELAXANTS (PERIPHERALLY-ACTING) AND CHOLINESTERASE INHIBITORS 21. OPHTHALMOLOGICAL PREPARATIONS 22. MEDICINES FOR REPRODUCTIVE HEALTH AND PERINATAL CARE 23. PERITONEAL DIALYSIS SOLUTION 24. MEDICINES FOR MENTAL AND BEHAVIOURAL DISORDERS 25. MEDICINES ACTING ON THE RESPIRATORY TRACT 26. SOLUTIONS CORRECTING WATER, ELECTROLYTE AND ACID-BASE DISTURBANCES 27. VITAMINS AND MINERALS 28. EAR, NOSE and THROAT MEDICINES 29. MEDICINES FOR DISEASES OF JOINTS 30. DENTAL PREPARATIONS