WHO Model List of Essential Medicines 2019 | List | Annotated Medicine and Device Lists

01. ANAESTHETICS, PREOPERATIVE MEDICINES AND MEDICAL GASES (2019)

Medicine	Pharmaceutical form type	Composition
halothane	inhalation	N/A
isoflurane	inhalation	N/A
nitrous oxide	inhalation	N/A
oxygen	inhalation (medicine gas)	N/A

Medicine	Pharmaceutical form type	Composition
ketamine	Injection	50 mg (as hydrochloride)/mL in 10-mL vial
propofol	Injection	20 mg/mL
propofol	Injection	10 mg/mL

Medicine	Pharmaceutical form type	Composition	Observation
bupivacaine	Injection for spinal anaesthesia	0.5% (hydrochloride) in 4-ml ampoule to be mixed with 7.5% glucose solution	e
bupivacaine	Injection	0.25% (hydrochloride) in vial	e
bupivacaine	Injection	0.5% (hydrochloride) in vial	e
lidocaine	Injection for spinal anaesthesia	5% (hydrochloride) in 2-ml ampoule to be mixed with 7.5% glucose solution	e
lidocaine	topical forms	2% to 4% (hydrochloride)	e
lidocaine	Injection	1% (hydrochloride) in vial	e
lidocaine	Injection	2% (hydrochloride) in vial	e
lidocaine + epinephrine (adrenaline)	Injection	2% (hydrochloride or sulfate) + epinephrine 1:200 000 in vial
lidocaine + epinephrine (adrenaline)	Injection	1% (hydrochloride or sulfate) + epinephrine 1:200 000 in vial
lidocaine + epinephrine (adrenaline)	dental cartridge	2% (hydrochloride) + epinephrine 1:80 000

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
ephedrine	Injection	30 mg (hydrochloride)/ml in 1-ml ampoule

Medicine	Pharmaceutical form type	Composition	Observation
atropine	Injection	1 mg (sulfate) in 1-ml ampoule
midazolam	Injection	1 mg/ml	e
midazolam	oral liquid	2 mg/ml	c2 e
midazolam	tablet	7.5 mg	e
midazolam	tablet	15 mg	e
morphine	Injection	10 mg (sulfate or hydrochloride) in 1-ml ampoule

Medicine	Pharmaceutical form type	Composition	Observation
oxygen	N/A	N/A

02. MEDICINES FOR PAIN AND PALLIATIVE CARE

Medicine	Pharmaceutical form type	Composition	Observation
acetylsalicylic acid	Suppository	50 mg to 150 mg
acetylsalicylic acid	tablet	100 mg to 500 mg
acetylsalicylic acid	Suppository	50 mg to 150 mg	c1
acetylsalicylic acid	tablet	100 mg to 500 mg	c1
ibuprofen	oral liquid	200 mg/5 mL	a
ibuprofen	tablet	200 mg	a
ibuprofen	tablet	400 mg	a
ibuprofen	tablet	600 mg
paracetamol	oral liquid	125 mg/5 ml
paracetamol	Suppository	100 mg
paracetamol	tablet	100 mg to 500 mg
paracetamol	oral liquid	120 mg/5 mL

Medicine	Pharmaceutical form type	Composition
codeine	tablet	30 mg (phosphate)
fentanyl	patch	12 mcg/hr
fentanyl	patch	25 mcg/hr
fentanyl	patch	50 mcg/hr
fentanyl	patch	75 mcg/hr
fentanyl	patch	100 mcg/hr
morphine	Injection	10 mg (sulfate or hydrochloride) in 1-ml ampoule
morphine	oral liquid	10 mg (hydrochloride or sulfate)/5 ml
morphine	tablet	10 mg - 200 mg (morphine sulfate)
morphine	tablet (prolonged release)	10 mg (morphine sulfate)
morphine	granules (modified release) (to mix with water)	200 mg
morphine	granules (modified release) (to mix with water)	20 mg

Complementary list

Medicine	Pharmaceutical form type	Composition
methadone	tablet	5mg
methadone	tablet	10mg
methadone	oral liquid	5 mg/5 ml (hydrochloride)
methadone	oral liquid	10 mg/5 ml (hydrochloride)
methadone	concentrate for oral liquid	5 mg/ml (hydrochloride)
methadone	concentrate for oral liquid	10 mg/ml (hydrochloride)

Medicine	Pharmaceutical form type	Composition	Observation
amitriptyline	tablet	10 mg
amitriptyline	tablet	25 mg
amitriptyline	tablet	75 mg
cyclizine	tablet	50 mg
cyclizine	Injection	50 mg/ml
dexamethasone	Injection	4 mg/mL in 1-mL ampoule (as disodium phosphate salt)
dexamethasone	oral liquid	2 mg/5 mL
dexamethasone	tablet	2 mg
dexamethasone	tablet	4 mg
dexamethasone	Injection	4 mg/mL in 1-mL ampoule (as disodium phosphate salt)
diazepam	Injection	5 mg/mL
diazepam	oral liquid	2 mg/5 mL
diazepam	rectal solution	2.5 mg
diazepam	rectal solution	5 mg
diazepam	rectal solution	10 mg
diazepam	tablet	5 mg
diazepam	tablet	10 mg
docusate sodium	capsule	100 mg
docusate sodium	oral liquid	50 mg/5 ml
fluoxetine	solid oral dosage form	20 mg (as hydrochloride)	a
haloperidol	Injection	5 mg/mL in 1-mL ampoule
haloperidol	oral liquid	2 mg/mL
haloperidol	solid oral dosage form	0.5 mg
haloperidol	solid oral dosage form	2 mg
haloperidol	solid oral dosage form	5 mg
hyoscine butylbromide	Injection	20 mg/ml
hyoscine hydrobromide	Injection	400 mcg/mL	c1
hyoscine hydrobromide	Injection	600 mcg/mL	c1
hyoscine hydrobromide	transdermal patches	1 mg/72 hours	c1
lactulose	oral liquid	3.1-3.7 g/5 ml	c1
loperamide	solid oral dosage form	2mg
metoclopramide	Injection	5 mg (hydrochloride)/mL in 2-mL ampoule
metoclopramide	oral liquid	5 mg/5 mL
metoclopramide	solid oral dosage form	10 mg (hydrochloride)
midazolam	Injection	1 mg/ml
midazolam	Injection	5 mg/mL
midazolam	solid oral dosage form	7.5 mg
midazolam	solid oral dosage form	15 mg
midazolam	oral liquid	2 mg/ml	c1
ondansetron	Injection	2 mg base/ml in 2-ml ampoule (as hydrochloride)	a c1
ondansetron	oral liquid	4 mg base/5 ml	a c1
ondansetron	solid oral dosage form	Eq 4 mg base	a c1
ondansetron	solid oral dosage form	Eq 8 mg base	a c1
senna	oral liquid	7.5 mg/5 ml

03. Antiallergics and medicines used in anaphylaxis

Medicine	Pharmaceutical form type	Composition	Observation
dexamethasone	Injection	4 mg/mL in 1-mL ampoule (as disodium phosphate salt)
epinephrine (adrenaline)	Injection	1 mg (as hydrochloride or hydrogen tartrate) in 1-ml ampoule
hydrocortisone	Powder for injection	100 mg (as sodium succinate) in vial
loratadine	tablet	10 mg	e
loratadine	oral liquid	1mg/ml	e
prednisolone	oral liquid	5 mg/mL	c2 e
prednisolone	tablet	5 mg	e
prednisolone	tablet	25 mg	e

04. Antidotes and other substances used in poisonings

Medicine	Pharmaceutical form type	Composition	Observation
charcoal, activated	Powder	N/A

Medicine	Pharmaceutical form type	Composition	Observation
acetylcysteine	Injection	200 mg/ml in 10-ml ampoule
acetylcysteine	oral liquid	10%	c2
acetylcysteine	oral liquid	20%	c2
atropine	Injection	1 mg (sulfate) in 1-ml ampoule
calcium gluconate	Injection	100 mg/mL in 10-mL ampoule
methylthioninium chloride (methylene blue)	Injection	10 mg/ml in 10-ml ampoule
naloxone	Injection	400 mcg (hydrochloride) in 1-mL ampoule
penicillamine	solid oral dosage form	250 mg
potassium ferric hexacyano-ferrate(II) - 2H20 (Prussian blue)	powder for oral administration	N/A
sodium nitrite	Injection	30 mg/mL in 10-mL ampoule
sodium thiosulfate	Injection	250 mg/mL in 50-mL ampoule

Complementary list

Medicine	Pharmaceutical form type	Composition
deferoxamine	Powder for injection	500 mg (mesilate) in vial
dimercaprol	Injection in oil	50 mg/mL in 2-mL ampoule
fomepizole	Injection	5 mg/ml (sulfate) in 20 ml ampoule or 1 g/ ml (base) in 1.5 ml ampoule
sodium calcium edetate	Injection	200 mg/ml in 5-ml ampoule
succimer	solid oral dosage form	100 mg

05. Anticonvulsants/antiepileptics

Medicine	Pharmaceutical form type	Composition	Observation
carbamazepine	oral liquid	100 mg/5 ml
carbamazepine	tablet (chewable)	100 mg
carbamazepine	tablet (chewable)	200 mg
carbamazepine	tablet (scored)	100 mg
carbamazepine	tablet (scored)	200 mg
diazepam	Gel	5 mg/mL in 0.5-mL tubes
diazepam	Gel	5 mg/mL in 2-mL tubes
diazepam	Gel	5 mg/mL in 4-mL tubes
diazepam	rectal solution	5 mg/mL in 0.5-mL tubes
diazepam	rectal solution	5 mg/mL in 2-mL tubes
diazepam	rectal solution	5 mg/mL in 4-mL tubes
lamotrigine	Chewable, dispersible	200 mg
lamotrigine	Chewable, dispersible	2 mg
lamotrigine	Chewable, dispersible	5 mg
lamotrigine	Chewable, dispersible	25 mg
lamotrigine	Chewable, dispersible	50 mg
lamotrigine	Chewable, dispersible	100 mg
lamotrigine	tablet	25 mg
lamotrigine	tablet	200 mg
lamotrigine	tablet	100 mg
lamotrigine	tablet	50 mg
lorazepam	parenteral formulation	2 mg/ml in 1-ml ampoule	e
lorazepam	parenteral formulation	4 mg/ml in 1-ml ampoule	e
magnesium sulfate	Injection	500 mg/mL in 2-mL ampoule
magnesium sulfate	Injection	500 mg/mL in 10-mL ampoule
midazolam	Oromucosal administration	5 mg/ ml
midazolam	Oromucosal administration	10 mg/ ml
midazolam	Ampoule	1 mg/ ml
midazolam	Ampoule	10 mg/ ml
phenobarbital	Injection	200 mg/mL (sodium)
phenobarbital	oral liquid	15 mg/5 mL
phenobarbital	tablet	15 mg to 100 mg
phenytoin	Injection	50 mg/mL in 5-mL vial (sodium salt)
phenytoin	oral liquid	25 mg to 30 mg/5 mL
phenytoin	solid oral dosage form	25 mg (sodium salt)
phenytoin	solid oral dosage form	50 mg (sodium salt)
phenytoin	solid oral dosage form	100 mg (sodium salt)
phenytoin	tablet (chewable)	50 mg
valproic acid (sodium valproate)	oral liquid	200 mg/5 ml
valproic acid (sodium valproate)	tablet (crushable)	100 mg
valproic acid (sodium valproate)	tablet (enteric-coated)	200 mg (sodium valproate)
valproic acid (sodium valproate)	tablet (enteric-coated)	500 mg (sodium valproate)

Complementary list

Medicine	Pharmaceutical form type	Composition
ethosuximide	capsule	250 mg
ethosuximide	oral liquid	250 mg/5 ml
valproic acid (sodium valproate)	Injection	100 mg/ml in 4 ml ampoule
valproic acid (sodium valproate)	Injection	100 mg/ml in 10 ml ampoule

06. Anti-infective medicines

Medicine	Pharmaceutical form type	Composition
albendazole	tablet (chewable)	400 mg
ivermectin	tablet (scored)	3 mg
levamisole	tablet	50 mg (as hydrochloride)
levamisole	tablet	150 mg (as hydrochloride)
mebendazole	tablet (chewable)	100 mg
mebendazole	tablet (chewable)	500 mg
niclosamide	tablet (chewable)	500 mg
praziquantel	tablet	150 mg
praziquantel	tablet	600 mg
pyrantel	oral liquid	50 mg (as embonate or pamoate)/ml
pyrantel	tablet (chewable)	250 mg (as embonate or pamoate)

Medicine	Pharmaceutical form type	Composition
albendazole	tablet (chewable)	400 mg
diethylcarbamazine	tablet	50 mg (dihydrogen citrate)
diethylcarbamazine	tablet	100 mg (dihydrogen citrate)
ivermectin	tablet (scored)	3 mg

Medicine	Pharmaceutical form type	Composition	Observation
praziquantel	tablet	600 mg
triclabendazole	tablet	250 mg

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
oxamniquine	capsule	250 mg
oxamniquine	oral liquid	250 mg/5 ml

Medicine	Pharmaceutical form type	Composition	Observation
amikacin	Injection	250 mg (as sulfate)/mL in 2-mL vial
amoxicillin	Powder for injection	250 mg (as sodium) in vial
amoxicillin	powder for oral liquid	125 mg (as trihydrate)/5 mL
amoxicillin	powder for oral liquid	250 mg (as trihydrate)/5 mL	c2
amoxicillin	solid oral dosage form	250 mg (as trihydrate)
amoxicillin	solid oral dosage form	500 mg (as trihydrate)
amoxicillin	Powder for injection	500 mg (as sodium) in vial
amoxicillin	Powder for injection	1 g (as sodium) in vial
amoxicillin	Powder for injection	250 mg (as sodium) in vial
amoxicillin + clavulanic acid	oral liquid	125 mg amoxicillin + 31.25 mg clavulanic acid/5 ml
amoxicillin + clavulanic acid	oral liquid	250 mg amoxicillin + 62.5 mg clavulanic acid/5 ml	c2
amoxicillin + clavulanic acid	tablet	500 mg (as trihydrate) + 125 mg (as potassium salt)
amoxicillin + clavulanic acid	Powder for injection	500 mg (as sodium) + 100 mg (as potassium salt) in vial
amoxicillin + clavulanic acid	Powder for injection	1000 mg (as sodium) + 200 mg (as potassium salt) in vial
ampicillin	Powder for injection	500 mg (as sodium salt) in vial
ampicillin	Powder for injection	1 g (as sodium salt) in vial
benzathine benzylpenicillin	Powder for injection	900 mg benzylpenicillin (= 1.2 million IU) in 5-ml vial	c2
benzathine benzylpenicillin	Powder for injection	1.44 g benzylpenicillin (= 2.4 million IU) in 5-ml vial
benzylpenicillin	Powder for injection	600 mg (= 1 million IU) (sodium or potassium salt) in vial
benzylpenicillin	Powder for injection	3 g (= 5 million IU) (sodium or potassium salt) in vial
cefalexin	powder for reconstitution with water	125 mg/5 mL (anhydrous)	c2
cefalexin	powder for reconstitution with water	250 mg/5 mL (anhydrous)	c2
cefalexin	solid oral dosage form	250 mg (as monohydrate)
cefazolin	Powder for injection	1 g (as sodium salt) in vial	a e
chloramphenicol	oral liquid	150 mg )as palmitate)/ 5 ml
chloramphenicol	Oily suspension for injection	0.5 g (as sodium succinate) / ml in 2 ml ampoule
chloramphenicol	Powder for injection	1 g (sodium succinate) in vial
Chloranfenicol	capsule	250 mg
clindamycin	capsule	150 mg (as hydrochloride)
clindamycin	Injection	150 mg (as phosphate)/mL
clindamycin	oral liquid	75 mg/5 mL (as palmitate)	c1
cloxacillin	capsule	500 mg (as sodium salt)	e
cloxacillin	capsule	1 g (as sodium salt)	e
cloxacillin	Powder for injection	500 mg (as sodium salt) in vial	e
cloxacillin	powder for oral liquid	125 mg (as sodium salt)/5 mL	e
doxycycline	oral liquid	25 mg/5 ml (anhydrous)	a c1
doxycycline	oral liquid	50 mg/5 ml (anhydrous)	a c1
doxycycline	solid oral dosage form	50 mg (as hyclate)	a c1
doxycycline	solid oral dosage form	100 mg (as hyclate)	c1
doxycycline	Powder for injection	100 mg	a c1
gentamicin	Injection	10 mg (sulfate)/mL in 2-mL vial
gentamicin	Injection	40 mg (sulfate)/ml in 2-mL vial
metronidazole	Injection	500 mg in 100-mL vial
metronidazole	oral liquid	200 mg (as benzoate)/5 mL
metronidazole	Suppository	500 mg
metronidazole	Suppository	1 g
metronidazole	tablet	200 mg to 500 mg
nitrofurantoin	oral liquid	25 mg/5 ml	c1
nitrofurantoin	tablet	100 mg
phenoxymethylpenicillin	powder for oral liquid	250 mg (as potassium salt)/5 ml
phenoxymethylpenicillin	tablet	250 mg (as potassium salt)
procaine benzylpenicillin	Powder for injection	1 g (=1 million IU) in vial
procaine benzylpenicillin	Powder for injection	3 g (=3 million IU) in vial
spectinomycin	Powder for injection	2 g (as hydrochloride) in vial
sulfamethoxazole + trimethoprim	Injection	80 mg + 16 mg/mL in 5-mL ampoule
sulfamethoxazole + trimethoprim	Injection	80 mg + 16 mg/mL in 10-mL ampoule
sulfamethoxazole + trimethoprim	oral liquid	200 mg + 40 mg/5 mL
sulfamethoxazole + trimethoprim	tablet	100 mg + 20 mg
sulfamethoxazole + trimethoprim	tablet	400 mg + 80 mg
sulfamethoxazole + trimethoprim	tablet	800 mg + 160 mg

Medicine	Pharmaceutical form type	Composition	Observation
azithromycin	capsule	250 mg (anhydrous)
azithromycin	capsule	500 mg (anhydrous)
azithromycin	oral liquid	200 mg/5 mL
cefixime	oral liquid	100 mg/ 5 ml	c1
cefixime	capsule	200 mg (as trihydrate)
cefixime	capsule	400 mg (as trihydrate)
cefotaxime	Powder for injection	250 mg per vial (as sodium salt)
ceftriaxone	Powder for injection	250 mg (as sodium salt) in vial	a
cefuroxime	Powder	1.5 g (as sodium salt) in vial
cefuroxime	Powder for injection	750 mg (as sodium salt) in vial
cefuroxime	Powder for injection	250 mg (as sodium salt) in vial
ciprofloxacin	oral liquid	250 mg/5 ml (anhydrous)	c2
ciprofloxacin	Solution for IV infusion	2 mg/ml (as hyclate)	c2
ciprofloxacin	tablet	250 mg (as hydrochloride)
clarithromycin	solid oral dosage form	500 mg
clarithromycin	Powder for injection	500 mg in vial
clarithromycin	powder for oral liquid	250 mg/ 5ml
clarithromycin	powder for oral liquid	125 mg/ 5ml
piperacillin sodium + tazobactum sodium	Powder for injection	4 g + 500 mg in vial
piperacillin sodium + tazobactum sodium	Powder for injection	2 g + 250 mg in vial
vancomycin	capsule	250 mg (as hydrochloride)
vancomycin	capsule	125 mg (as hydrochloride)

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
ceftazidime	Powder for injection	250 mg or 1 g (as pentahydrate) in vial
meropenem	Powder for injection	1 g (as trihydrate) in vial	a
meropenem	Powder for injection	500 mg (as trihydrate) in vial	a
vancomycin	Powder for injection	250 mg (as hydrochloride) in vial

Medicine	Pharmaceutical form type	Composition	Observation

Complementary list

Medicine	Pharmaceutical form type	Composition
ceftazidime + avibactam	Powder for injection	2 g + 0,5 g in vial
colistine	Powder for injection	1 million I.U. (as colistemethate sodium) in vial
linezolid	tablet	400 mg
linezolid	tablet	600 mg
linezolid	injection for intravenous administration	2 mg/ ml in 300 ml bag
linezolid	powder for oral liquid	100 mg/ 5 ml
meropenem + vaborbactam	Powder for injection	1 g + 1 g in vial
phosphomycin	Powder for injection	2 g (as sodium) in vial
phosphomycin	Powder for injection	4 g (as sodium) in vial
plazomicin	Injection	500 mg/ 10 ml
polymyxin B	Powder for injection	500.000 I.U. in vial

Medicines used in the treatment of leprosy should never be used except in combination. Combination therapy is essential to prevent the emergence of drug resistance. Colour coded blister packs (MDT blister packs) containing standard two medicine (paucibacillary leprosy) or three medicine (multibacillary leprosy) combinations for adult and childhood leprosy should be used. MDT blister packs can be supplied free of charge through WHO.

Medicine	Pharmaceutical form type	Composition
clofazimine	capsule	50 mg
clofazimine	capsule	100 mg
dapsone	tablet	25 mg
dapsone	tablet	50 mg
dapsone	tablet	100 mg
rifampicin	solid oral dosage form	150 mg
rifampicin	solid oral dosage form	300 mg

Medicine	Pharmaceutical form type	Composition	Observation
ethambutol	tablet (dispersible)	100 mg	c1
ethambutol	oral liquid	25 mg/ml	c2
ethambutol	tablet	100 mg to 400 mg (hydrochloride)
ethambutol + isoniazid + pyrazinamide + rifampicin	tablet	275 mg + 75 mg + 400 mg + 150 mg
ethambutol + isoniazid + rifampicin	tablet	275 mg + 75 mg + 150 mg
isoniazid	tablet (dispersible)	100 mg	c1
isoniazid	oral liquid	50 mg/5 ml	c2
isoniazid	tablet	100 mg to 300 mg
isoniazid	tablet (scored)	50 mg
isoniazid + pyrazinamide + rifampicin	tablet (dispersible)	50 mg + 150 mg + 75 mg	c1
isoniazid + pyrazinamide + rifampicin	tablet	75 mg + 400 mg + 150 mg
isoniazid + rifampicin	tablet (dispersible)	50 mg + 75 mg	c1
isoniazid + rifampicin	tablet	75 mg + 150 mg
isoniazid + rifampicin	tablet	150 mg + 300 mg
pyrazinamide	oral liquid	30 mg/ml	c2
pyrazinamide	tablet	400 mg
pyrazinamide	tablet (dispersible)	150 mg
pyrazinamide	tablet (scored)	150 mg
rifabutin	solid oral dosage form	150 mg
rifampicin	oral liquid	20 mg/ml	c2
rifampicin	solid oral dosage form	150 mg
rifampicin	solid oral dosage form	300 mg
rifapentine	tablet	150 mg

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
amikacin	Powder for injection	100 mg (as sulfate) in vial
amikacin	Powder for injection	500 mg (as sulfate) in vial
amikacin	Powder for injection	1 g (as sulfate) in vial
amoxicillin + clavulanic acid	tablet	500mg + 125mg
amoxicillin + clavulanic acid	oral liquid	125 mg amoxicillin + 31.25 mg clavulanic acid/5 ml	c1
amoxicillin + clavulanic acid	oral liquid	250 mg amoxicillin + 62.5 mg clavulanic acid/5 ml	c1
bedaquilina	tablet	100 mg	a
clofazimine	solid oral dosage form	50 mg
clofazimine	solid oral dosage form	100 mg
cycloserine	solid oral dosage form	125 mg	c1
cycloserine	solid oral dosage form	250 mg
delamanid	tablet	50 mg	a
ethionamide	tablet	125 mg
ethionamide	tablet	250 mg
ethionamide	tablet (dispersible)	125 mg	c1
levofloxacin	tablet	250 mg
levofloxacin	tablet	500 mg
levofloxacin	tablet	750 mg
levofloxacin	tablet (dispersible)	100 mg	c1
linezolid	injection for intravenous administration	2 mg/ ml in 300 ml bag
linezolid	powder for oral liquid	100 mg/ 5 ml
linezolid	tablet	400 mg
linezolid	tablet	600 mg
linezolid	tablet (dispersible)	150 mg	c1
meropenem	Powder for injection	500 mg (as trihydrate) in vial
meropenem	Powder for injection	1 g (as trihydrate) in vial
moxifloxacin	tablet	400 mg
moxifloxacin	tablet (dispersible)	100 mg	c1
p-aminosalicylic acid	granules	4 g in sachet
p-aminosalicylic acid	tablet	500 mg
streptomycin	Powder for injection	1 g (as sulfate) in vial	c1

Medicine	Pharmaceutical form type	Composition	Observation
amphotericin B	Powder for injection	50 mg in vial
clotrimazole	vaginal cream	1%
clotrimazole	vaginal cream	10%
clotrimazole	vaginal tablet	100 mg
clotrimazole	vaginal tablet	500 mg
fluconazole	capsule	50 mg
fluconazole	Injection	2 mg/mL in vial
fluconazole	oral liquid	50 mg/5 mL
flucytosine	capsule	250 mg
flucytosine	Infusion	2.5 g in 250 ml
griseofulvin	oral liquid	125 mg/5 ml	c2
griseofulvin	solid oral dosage form	125 mg
griseofulvin	solid oral dosage form	250 mg
itraconazole	oral liquid	10 mg/ ml
itraconazole	capsule	100 mg
nystatin	Lozenge	100 000 IU
nystatin	oral liquid	50 mg/5 ml	c1
nystatin	oral liquid	100 000 IU/ml	c1
nystatin	pessary	100 000 IU
nystatin	tablet	100 000 IU
nystatin	tablet	500 000 IU
voriconazol	tablet	50 mg
voriconazol	tablet	200 mg
voriconazol	Powder for injection	200 mg in vial
voriconazol	powder for oral liquid	40 mg/ ml

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
potassium iodide	saturated solution	N/A

Medicine	Pharmaceutical form type	Composition	Observation
aciclovir	oral liquid	200 mg/5 mL	e
aciclovir	Powder for injection	250 mg (as sodium salt) in vial	e
aciclovir	tablet	200 mg	e

Based on current evidence and experience of use, medicines in the following three classes of antiretrovirals are included as essential medicines for treatment and prevention of HIV (prevention of mother-to-child transmission and post-exposure prophylaxis). The Committee emphasizes the importance of using these products in accordance with global and national guidelines. The Committee recommends and endorses the use of fixed-dose combinations and the development of appropriate new fixed-dose combinations, including modified dosage forms, non-refrigerated products and paediatric dosage forms of assured pharmaceutical quality. Scored tablets can be used in children and therefore can be considered for inclusion in the listing of tablets, provided adequate quality products are available.

Medicine	Pharmaceutical form type	Composition	Observation
abacavir (ABC)	tablet	300 mg (as sulfate)
lamivudine (3TC)	oral liquid	50 mg/5 ml	c1
lamivudine (3TC)	tablet	150 mg
tenofovir disoproxil fumarate	tablet	300 mg
zidovudine (ZDV or AZT)	capsule	250 mg
zidovudine (ZDV or AZT)	oral liquid	50 mg/5 mL
zidovudine (ZDV or AZT)	Solution for IV infusion injection	10 mg/mL in 20-mL vial
zidovudine (ZDV or AZT)	tablet	300 mg

Medicine	Pharmaceutical form type	Composition	Observation
efavirenz (EFV or EFZ)	tablet	200 mg	a
efavirenz (EFV or EFZ)	tablet	600 mg	a
nevirapine (NVP)	tablet (dispersible)	50 mg	a
nevirapine (NVP)	oral liquid	50 mg/5 ml	a
nevirapine (NVP)	tablet	200 mg	a

Selection of protease inhibitor(s) from the Model List will need to be determined by each country after consideration of international and national treatment guidelines and experience. Ritonavir is recommended for use in combination as a pharmacological booster, and not as an antiretroviral in its own right. All other protease inhibitors should be used in boosted forms (e.g. with ritonavir).

Medicine	Pharmaceutical form type	Composition	Observation
atazanavir	solid oral dosage form	100 mg (as sulfate)	a
atazanavir	solid oral dosage form	300 mg (as sulfate)	a
atazanavir + ritonavir	tablet (heat stable)	300 mg (as sulfate) + 100 mg
darunavir	tablet	800 mg	a
darunavir	tablet	600 mg	a
darunavir	tablet	400 mg	a
darunavir	tablet	75 mg	a
lopinavir + ritonavir (LPV/r)	oral liquid	400 mg + 100 mg/5 ml
lopinavir + ritonavir (LPV/r)	tablet (heat stable)	100 mg + 25 mg
lopinavir + ritonavir (LPV/r)	tablet (heat stable)	200 mg + 50 mg
lopinavir + ritonavir (LPV/r)	solid oral dosage form	40 mg + 10 mg	c1
ritonavir	oral liquid	400 mg/5 ml
ritonavir	tablet (heat stable)	25 mg
ritonavir	tablet (heat stable)	100 mg
ritonavir	oral powder	100 mg in sachet	c1

Medicine	Pharmaceutical form type	Composition	Observation
dolutegravir	tablet	50 mg	a
raltegavir	tablet	400 mg
raltegavir	tablet (chewable)	25 mg
raltegavir	tablet (chewable)	100 mg
raltegavir	granules	100 mg in sachet

Medicine	Pharmaceutical form type	Composition
dasabuvir	tablet	250 mg
ledipasvir + sofosbuvir	tablet	90 mg/ 400 mg
ombitasvir + paritaprevir + ritonavir	tablet	12.5 mg + 75 mg + 50 mg

Medicine	Pharmaceutical form type	Composition	Observation
abacavir + lamivudine	tablet (dispersible)	120 mg (as sulfate) + 60 mg
dolutegravir + lamivudina + tenofovir disoproxil	tablet (enteric-coated)	50 mg + 300 mg + 245 mg
efavirenz + emtricitabine + tenofovir	tablet	600 mg + 200 mg + 300 mg
emtricitabine + tenofovir	tablet	200 mg + 300 mg
lamivudine + nevirapine + zidovudine	tablet	30 mg + 50 mg + 60 mg	c1
lamivudine + nevirapine + zidovudine	tablet	150 mg + 200 mg + 300 mg
lamivudine + zidovudine	tablet	30 mg + 60 mg	c1
lamivudine + zidovudine	tablet	150 mg + 300 mg
tenofovir disoproxilo + efavirenz + lamivudine	tablet	300 mg + 400 mg + 300 mg

Medicine	Pharmaceutical form type	Composition	Observation
isoniazid + pyridoxine + sulfamethoxazole + trimethoprim	tablet (scored)	300 mg + 25 mg + 800 mg + 160 mg

Medicine	Pharmaceutical form type	Composition
ribavirin	injection for intravenous administration	800 mg in 10-ml phosphate buffer solution
ribavirin	injection for intravenous administration	1 g in 10-ml phosphate buffer solution
ribavirin	solid oral dosage form	200 mg
ribavirin	solid oral dosage form	400 mg
ribavirin	solid oral dosage form	600 mg
valgancyclovir	tablet	450mg

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
oseltamivir	capsule	30 mg (as phosphate)
oseltamivir	capsule	45 mg (as phosphate)
oseltamivir	capsule	75 mg (as phosphate)
oseltamivir	oral powder	12 mg/mL
valganciclovir	Powder for solution	50 mg/ ml	c1
valgancyclovir	tablet	450mg	c1

Medicine	Pharmaceutical form type	Composition
entecavir	oral liquid	0.05 mg/ ml
entecavir	tablet	1 mg
entecavir	tablet	0.05 mg
tenofovir disoproxil fumarate	tablet	300 mg

Medicine	Pharmaceutical form type	Composition
daclatasvir	tablet	60 mg (as hydrochloride)
daclatasvir	tablet	30 mg (as hydrochloride)
glecaprevir + pibrentasvir	tablet	100 mg + 40 mg
sofosbuvir	tablet	400 mg
sofosbuvir + velpatasvir	tablet (enteric-coated)	400 mg + 100 mg.

Medicine	Pharmaceutical form type	Composition	Observation