WHO Model List of Essential Medicines 2019 | List | Annotated Medicine and Device Lists

01. ANAESTHETICS, PREOPERATIVE MEDICINES AND MEDICAL GASES (2019)

Medicine	Pharmaceutical form type	Composition
oxygen	inhalation (medicine gas)	N/A
nitrous oxide	inhalation	N/A
isoflurane	inhalation	N/A
halothane	inhalation	N/A

Medicine	Pharmaceutical form type	Composition
propofol	Injection	20 mg/mL
propofol	Injection	10 mg/mL
ketamine	Injection	50 mg (as hydrochloride)/mL in 10-mL vial

Medicine	Pharmaceutical form type	Composition	Observation
lidocaine + epinephrine (adrenaline)	Injection	2% (hydrochloride or sulfate) + epinephrine 1:200 000 in vial
lidocaine + epinephrine (adrenaline)	Injection	1% (hydrochloride or sulfate) + epinephrine 1:200 000 in vial
lidocaine	Injection for spinal anaesthesia	5% (hydrochloride) in 2-ml ampoule to be mixed with 7.5% glucose solution	e
lidocaine	topical forms	2% to 4% (hydrochloride)	e
lidocaine + epinephrine (adrenaline)	dental cartridge	2% (hydrochloride) + epinephrine 1:80 000
bupivacaine	Injection for spinal anaesthesia	0.5% (hydrochloride) in 4-ml ampoule to be mixed with 7.5% glucose solution	e
lidocaine	Injection	1% (hydrochloride) in vial	e
lidocaine	Injection	2% (hydrochloride) in vial	e
bupivacaine	Injection	0.25% (hydrochloride) in vial	e
bupivacaine	Injection	0.5% (hydrochloride) in vial	e

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
ephedrine	Injection	30 mg (hydrochloride)/ml in 1-ml ampoule

Medicine	Pharmaceutical form type	Composition	Observation
atropine	Injection	1 mg (sulfate) in 1-ml ampoule
midazolam	Injection	1 mg/ml	e
midazolam	oral liquid	2 mg/ml	c2 e
midazolam	tablet	7.5 mg	e
midazolam	tablet	15 mg	e
morphine	Injection	10 mg (sulfate or hydrochloride) in 1-ml ampoule

02. Analgesics, antipyretics, non-steroidal anti-inflammatory medicines (NSAIMs), medicines used to treat gout and disease modifying agents in rheumatoid disorders (DMARDs)

Medicine	Pharmaceutical form type	Composition	Observation
acetylsalicylic acid	Suppository	50 mg to 150 mg
acetylsalicylic acid	tablet	100 mg to 500 mg
ibuprofen	oral liquid	200 mg/5 mL	a
ibuprofen	tablet	200 mg	a
ibuprofen	tablet	400 mg	a
paracetamol	oral liquid	125 mg/5 ml
paracetamol	Suppository	100 mg
paracetamol	tablet	100 mg to 500 mg

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
acetylsalicylic acid	Suppository	50 mg to 150 mg	c1
acetylsalicylic acid	tablet	100 mg to 500 mg	c1

Medicine	Pharmaceutical form type	Composition
codeine	tablet	30 mg (phosphate)
morphine	Injection	10 mg (sulfate or hydrochloride) in 1-ml ampoule
morphine	oral liquid	10 mg (hydrochloride or sulfate)/5 ml
morphine	tablet	10 mg (morphine sulfate)
morphine	tablet (prolonged release)	10 mg (morphine sulfate)
morphine	tablet (prolonged release)	30 mg (morphine sulfate)
morphine	tablet (prolonged release)	60 mg (morphine sulfate)

Medicine	Pharmaceutical form type	Composition	Observation
allopurinol	tablet	100 mg

Medicine	Pharmaceutical form type	Composition	Observation
chloroquine	tablet	100 mg (as phosphate or sulfate)
chloroquine	tablet	150 mg (as phosphate or sulfate)

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
azithromycin	powder for oral suspension	200 mg
hydroxychloroquine	solid oral dosage form	200 mg (as sulfate)	c1
methotrexate	tablet	2.5 mg (as sodium salt)
penicillamine	solid oral dosage form	250 mg
sulfasalazine	tablet	500 mg

03. Antiallergics and medicines used in anaphylaxis

Medicine	Pharmaceutical form type	Composition	Observation
chlorphenamine	Injection	10 mg (hydrogen maleate) in 1-ml ampoule	a e
chlorphenamine	oral liquid	2 mg/5 ml (hydrogen maleate)	a c2 e
chlorphenamine	tablet	4 mg (hydrogen maleate)	a e
dexamethasone	Injection	4 mg/mL in 1-mL ampoule (as disodium phosphate salt)
epinephrine (adrenaline)	Injection	1 mg (as hydrochloride or hydrogen tartrate) in 1-ml ampoule
hydrocortisone	Powder for injection	100 mg (as sodium succinate) in vial
prednisolone	oral liquid	5 mg/mL	c2 e
prednisolone	tablet	5 mg	e
prednisolone	tablet	25 mg	e

04. Antidotes and other substances used in poisonings

Medicine	Pharmaceutical form type	Composition	Observation
charcoal, activated	Powder	N/A

Medicine	Pharmaceutical form type	Composition	Observation
acetylcysteine	Injection	200 mg/ml in 10-ml ampoule
acetylcysteine	oral liquid	10%	c2
acetylcysteine	oral liquid	20%	c2
atropine	Injection	1 mg (sulfate) in 1-ml ampoule
calcium gluconate	Injection	100 mg/mL in 10-mL ampoule
methylthioninium chloride (methylene blue)	Injection	10 mg/ml in 10-ml ampoule
naloxone	Injection	400 mcg (hydrochloride) in 1-mL ampoule
penicillamine	solid oral dosage form	250 mg
potassium ferric hexacyano-ferrate(II) - 2H20 (Prussian blue)	powder for oral administration	N/A
sodium nitrite	Injection	30 mg/mL in 10-mL ampoule
sodium thiosulfate	Injection	250 mg/mL in 50-mL ampoule

Complementary list

Medicine	Pharmaceutical form type	Composition
deferoxamine	Powder for injection	500 mg (mesilate) in vial
dimercaprol	Injection in oil	50 mg/mL in 2-mL ampoule
sodium calcium edetate	Injection	200 mg/ml in 5-ml ampoule
succimer	solid oral dosage form	100 mg

05. Anticonvulsants/antiepileptics

Medicine	Pharmaceutical form type	Composition	Observation
carbamazepine	oral liquid	100 mg/5 ml
carbamazepine	tablet (chewable)	100 mg
carbamazepine	tablet (chewable)	200 mg
carbamazepine	tablet (scored)	100 mg
carbamazepine	tablet (scored)	200 mg
diazepam	Gel	5 mg/mL in 0.5-mL tubes
diazepam	Gel	5 mg/mL in 2-mL tubes
diazepam	Gel	5 mg/mL in 4-mL tubes
lorazepam	parenteral formulation	2 mg/ml in 1-ml ampoule	e
lorazepam	parenteral formulation	4 mg/ml in 1-ml ampoule	e
magnesium sulfate	Injection	500 mg/mL in 2-mL ampoule
magnesium sulfate	Injection	500 mg/mL in 10-mL ampoule
phenobarbital	Injection	200 mg/mL (sodium)
phenobarbital	oral liquid	15 mg/5 mL
phenobarbital	tablet	15 mg to 100 mg
phenytoin	Injection	50 mg/mL in 5-mL vial (sodium salt)
phenytoin	oral liquid	25 mg to 30 mg/5 mL
phenytoin	solid oral dosage form	25 mg (sodium salt)
phenytoin	solid oral dosage form	50 mg (sodium salt)
phenytoin	solid oral dosage form	100 mg (sodium salt)
phenytoin	tablet (chewable)	50 mg
valproic acid (sodium valproate)	oral liquid	200 mg/5 ml
valproic acid (sodium valproate)	tablet (crushable)	100 mg
valproic acid (sodium valproate)	tablet (enteric-coated)	200 mg (sodium valproate)
valproic acid (sodium valproate)	tablet (enteric-coated)	500 mg (sodium valproate)
diazepam	rectal solution	5 mg/mL in 0.5-mL tubes
diazepam	rectal solution	5 mg/mL in 2-mL tubes
diazepam	rectal solution	5 mg/mL in 4-mL tubes

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
ethosuximide	capsule	250 mg
ethosuximide	oral liquid	250 mg/5 ml

06. Anti-infective medicines

Medicine	Pharmaceutical form type	Composition
albendazole	tablet (chewable)	400 mg
levamisole	tablet	50 mg (as hydrochloride)
levamisole	tablet	150 mg (as hydrochloride)
mebendazole	tablet (chewable)	100 mg
mebendazole	tablet (chewable)	500 mg
niclosamide	tablet (chewable)	500 mg
praziquantel	tablet	150 mg
praziquantel	tablet	600 mg
pyrantel	oral liquid	50 mg (as embonate or pamoate)/ml
pyrantel	tablet (chewable)	250 mg (as embonate or pamoate)

Medicine	Pharmaceutical form type	Composition
albendazole	tablet (chewable)	400 mg
diethylcarbamazine	tablet	50 mg (dihydrogen citrate)
diethylcarbamazine	tablet	100 mg (dihydrogen citrate)
ivermectin	tablet (scored)	3 mg
ivermectin	tablet (scored)	6 mg

Medicine	Pharmaceutical form type	Composition	Observation
praziquantel	tablet	600 mg
triclabendazole	tablet	250 mg

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
oxamniquine	capsule	250 mg
oxamniquine	oral liquid	250 mg/5 ml

Medicine	Pharmaceutical form type	Composition	Observation
amoxicillin	powder for oral liquid	125 mg (as trihydrate)/5 mL
amoxicillin	powder for oral liquid	250 mg (as trihydrate)/5 mL	c2
amoxicillin	solid oral dosage form	250 mg (as trihydrate)
amoxicillin	solid oral dosage form	500 mg (as trihydrate)
amoxicillin + clavulanic acid	oral liquid	125 mg amoxicillin + 31.25 mg clavulanic acid/5 ml
amoxicillin + clavulanic acid	oral liquid	250 mg amoxicillin + 62.5 mg clavulanic acid/5 ml	c2
amoxicillin + clavulanic acid	tablet	500 mg (as trihydrate) + 125 mg (as potassium salt)
ampicillin	Powder for injection	500 mg (as sodium salt) in vial
ampicillin	Powder for injection	1 g (as sodium salt) in vial
benzathine benzylpenicillin	Powder for injection	900 mg benzylpenicillin (= 1.2 million IU) in 5-ml vial	c2
benzathine benzylpenicillin	Powder for injection	1.44 g benzylpenicillin (= 2.4 million IU) in 5-ml vial
benzylpenicillin	Powder for injection	600 mg (= 1 million IU) (sodium or potassium salt) in vial
benzylpenicillin	Powder for injection	3 g (= 5 million IU) (sodium or potassium salt) in vial
cefalexin	powder for reconstitution with water	125 mg/5 mL (anhydrous)	c2
cefalexin	powder for reconstitution with water	250 mg/5 mL (anhydrous)	c2
cefazolin	Powder for injection	1 g (as sodium salt) in vial	a e
cefixime	capsule	400 mg (as trihydrate)
ceftriaxone	Powder for injection	250 mg (as sodium salt) in vial	a
ceftriaxone	Powder for injection	1 g (as sodium salt) in vial	a
cloxacillin	capsule	500 mg (as sodium salt)	e
cloxacillin	capsule	1 g (as sodium salt)	e
cloxacillin	Powder for injection	500 mg (as sodium salt) in vial	e
cloxacillin	powder for oral liquid	125 mg (as sodium salt)/5 mL	e
phenoxymethylpenicillin	powder for oral liquid	250 mg (as potassium salt)/5 ml
phenoxymethylpenicillin	tablet	250 mg (as potassium salt)
procaine benzylpenicillin	Powder for injection	1 g (=1 million IU) in vial
procaine benzylpenicillin	Powder for injection	3 g (=3 million IU) in vial

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
cefotaxime	Powder for injection	250 mg per vial (as sodium salt)	c1
ceftazidime	Powder for injection	250 mg (as pentahydrate) in vial
ceftazidime	Powder for injection	1 g (as pentahydrate) in vial
imipenem + cilastatin	Powder for injection	250 mg (as monohydrate) + 250 mg (as sodium salt) in vial
imipenem + cilastatin	Powder for injection	500 mg (as monohydrate) + 500 mg (as sodium salt) in vial

Medicine	Pharmaceutical form type	Composition	Observation
azithromycin	capsule	250 mg (anhydrous)
azithromycin	capsule	500 mg (anhydrous)
azithromycin	oral liquid	200 mg/5 mL
chloramphenicol	capsule	250 mg
chloramphenicol	Oily suspension for injection	0.5 g (as sodium succinate)/ml in 2-ml ampoule
chloramphenicol	oral liquid	150 mg (as palmitate)/5 mL
chloramphenicol	Powder for injection	1 g (sodium succinate) in vial
ciprofloxacin	oral liquid	250 mg/5 ml (anhydrous)	c2 e
ciprofloxacin	Solution for IV infusion	2 mg/ml (as hyclate)	c2 e
ciprofloxacin	tablet	250 mg (as hydrochloride)	e
clarithromycin	solid oral dosage form	500 mg
doxycycline	oral liquid	25 mg/5 ml (anhydrous)	a c2
doxycycline	oral liquid	50 mg/5 ml (anhydrous)	a c2
doxycycline	solid oral dosage form	50 mg (as hyclate)	a c2
doxycycline	solid oral dosage form	100 mg (as hyclate)	a
erythromycin	Powder for injection	500 mg (as lactobionate) in vial	e
erythromycin	powder for oral liquid	125 mg/5 mL (as stearate or estolate or ethyl succinate)	e
erythromycin	solid oral dosage form	250 mg (as stearate or estolate or ethyl succinate)	e
gentamicin	Injection	10 mg (sulfate)/mL in 2-mL vial	e
gentamicin	Injection	40 mg (sulfate)/ml in 2-mL vial
metronidazole	Injection	500 mg in 100-mL vial	e
metronidazole	oral liquid	200 mg (as benzoate)/5 mL	e
metronidazole	Suppository	500 mg	e
metronidazole	Suppository	1 g	e
metronidazole	tablet	200 mg to 500 mg	e
nitrofurantoin	oral liquid	25 mg/5 ml	c2
nitrofurantoin	tablet	100 mg
spectinomycin	Powder for injection	2 g (as hydrochloride) in vial
sulfamethoxazole + trimethoprim	Injection	80 mg + 16 mg/mL in 5-mL ampoule
sulfamethoxazole + trimethoprim	Injection	80 mg + 16 mg/mL in 10-mL ampoule
sulfamethoxazole + trimethoprim	oral liquid	200 mg + 40 mg/5 mL
sulfamethoxazole + trimethoprim	tablet	100 mg + 20 mg
sulfamethoxazole + trimethoprim	tablet	400 mg + 80 mg
sulfamethoxazole + trimethoprim	tablet	800 mg + 160 mg
trimethoprim	oral liquid	50 mg/5 ml	a c2
trimethoprim	tablet	100 mg	a
trimethoprim	tablet	200 mg	a
clindamycin	oral liquid	75 mg/5 mL (as palmitate)	c2
vancomycin	Powder for injection	250 mg (as hydrochloride) in vial

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
clindamycin	capsule	150 mg (as hydrochloride)
clindamycin	Injection	150 mg (as phosphate)/mL

Medicines used in the treatment of leprosy should never be used except in combination. Combination therapy is essential to prevent the emergence of drug resistance. Colour coded blister packs (MDT blister packs) containing standard two medicine (paucibacillary leprosy) or three medicine (multibacillary leprosy) combinations for adult and childhood leprosy should be used. MDT blister packs can be supplied free of charge through WHO.

Medicine	Pharmaceutical form type	Composition
clofazimine	capsule	50 mg
clofazimine	capsule	100 mg
dapsone	tablet	25 mg
dapsone	tablet	50 mg
dapsone	tablet	100 mg
rifampicin	solid oral dosage form	150 mg
rifampicin	solid oral dosage form	300 mg

Medicine	Pharmaceutical form type	Composition	Observation
ethambutol	oral liquid	25 mg/ml	c2
ethambutol	tablet	100 mg to 400 mg (hydrochloride)
ethambutol + isoniazid	tablet	400 mg + 150 mg
ethambutol + isoniazid + pyrazinamide + rifampicin	tablet	275 mg + 75 mg + 400 mg + 150 mg
ethambutol + isoniazid + rifampicin	tablet	275 mg + 75 mg + 150 mg
isoniazid	oral liquid	50 mg/5 ml	c2
isoniazid	tablet	100 mg to 300 mg
isoniazid	tablet (scored)	50 mg
isoniazid + pyrazinamide + rifampicin	tablet	75 mg + 400 mg + 150 mg
isoniazid + pyrazinamide + rifampicin	tablet	150 mg + 500 mg + 150 mg
isoniazid + rifampicin	tablet	75 mg + 150 mg
isoniazid + rifampicin	tablet	150 mg + 300 mg
isoniazid + rifampicin	tablet	60 mg + 60 mg
isoniazid + rifampicin	tablet	150 mg + 150 mg
pyrazinamide	oral liquid	30 mg/ml	c2
pyrazinamide	tablet	400 mg
pyrazinamide	tablet (dispersible)	150 mg
pyrazinamide	tablet (scored)	150 mg
rifabutin	capsule	150 mg
rifampicin	oral liquid	20 mg/ml	c2
rifampicin	solid oral dosage form	150 mg
rifampicin	solid oral dosage form	300 mg
streptomycin	Powder for injection	1 g (as sulfate) in vial

Complementary list

Medicine	Pharmaceutical form type	Composition
amikacin	Powder for injection	100 mg (as sulfate) in vial
amikacin	Powder for injection	500 mg (as sulfate) in vial
amikacin	Powder for injection	1 g (as sulfate) in vial
capreomycin	Powder for injection	1 g (as sulfate) in vial
cycloserine	solid oral dosage form	250 mg
ethionamide	tablet	125 mg
ethionamide	tablet	250 mg
kanamycin	Powder for injection	1 g (as sulfate) in vial
ofloxacin	tablet	200 mg
ofloxacin	tablet	400 mg
p-aminosalicylic acid	granules	4 g in sachet
p-aminosalicylic acid	tablet	500 mg

Medicine	Pharmaceutical form type	Composition	Observation
clotrimazole	vaginal cream	1%
clotrimazole	vaginal cream	10%
clotrimazole	vaginal tablet	100 mg
clotrimazole	vaginal tablet	500 mg
fluconazole	capsule	50 mg	e
fluconazole	Injection	2 mg/mL in vial	e
fluconazole	oral liquid	50 mg/5 mL	e
griseofulvin	oral liquid	125 mg/5 ml	c2
griseofulvin	solid oral dosage form	125 mg
griseofulvin	solid oral dosage form	250 mg
nystatin	Lozenge	100 000 IU
nystatin	oral liquid	50 mg/5 ml	c2
nystatin	oral liquid	100 000 IU/ml	c2
nystatin	pessary	100 000 IU
nystatin	tablet	100 000 IU
nystatin	tablet	500 000 IU

Complementary list

Medicine	Pharmaceutical form type	Composition
amphotericin B	Powder for injection	50 mg in vial
flucytosine	capsule	250 mg
flucytosine	Infusion	2.5 g in 250 ml
potassium iodide	saturated solution	N/A

Medicine	Pharmaceutical form type	Composition	Observation
aciclovir	oral liquid	200 mg/5 mL	e
aciclovir	Powder for injection	250 mg (as sodium salt) in vial	e
aciclovir	tablet	200 mg	e

Based on current evidence and experience of use, medicines in the following three classes of antiretrovirals are included as essential medicines for treatment and prevention of HIV (prevention of mother-to-child transmission and post-exposure prophylaxis). The Committee emphasizes the importance of using these products in accordance with global and national guidelines. The Committee recommends and endorses the use of fixed-dose combinations and the development of appropriate new fixed-dose combinations, including modified dosage forms, non-refrigerated products and paediatric dosage forms of assured pharmaceutical quality. Scored tablets can be used in children and therefore can be considered for inclusion in the listing of tablets, provided adequate quality products are available.

Medicine	Pharmaceutical form type	Composition	Observation
abacavir (ABC)	oral liquid	100 mg (as sulfate)/5 ml
abacavir (ABC)	tablet	300 mg (as sulfate)
didanosine (ddI)	buffered powder for oral liquid	100 mg packets
didanosine (ddI)	buffered powder for oral liquid	167 mg packets
didanosine (ddI)	buffered powder for oral liquid	250 mg packets
didanosine (ddI)	capsule (unbuffered enteric-coated)	125 mg
didanosine (ddI)	capsule (unbuffered enteric-coated)	200 mg
didanosine (ddI)	capsule (unbuffered enteric-coated)	250 mg
didanosine (ddI)	capsule (unbuffered enteric-coated)	400 mg
didanosine (ddI)	tablet (buffered chewable, dispersible)	25 mg
didanosine (ddI)	tablet (buffered chewable, dispersible)	50 mg
didanosine (ddI)	tablet (buffered chewable, dispersible)	100 mg
didanosine (ddI)	tablet (buffered chewable, dispersible)	150 mg
didanosine (ddI)	tablet (buffered chewable, dispersible)	200 mg
emtricitabine (FTC)	capsule	200 mg	a
emtricitabine (FTC)	oral liquid	10 mg/ml	a
lamivudine (3TC)	oral liquid	50 mg/5 ml
lamivudine (3TC)	tablet	150 mg
stavudine (d4T)	capsule	15 mg
stavudine (d4T)	capsule	20 mg
stavudine (d4T)	capsule	30 mg
stavudine (d4T)	powder for oral liquid	5 mg/5 ml
tenofovir disoproxil fumarate	tablet	300 mg
zidovudine (ZDV or AZT)	capsule	100 mg
zidovudine (ZDV or AZT)	capsule	250 mg
zidovudine (ZDV or AZT)	oral liquid	50 mg/5 mL
zidovudine (ZDV or AZT)	Solution for IV infusion injection	10 mg/mL in 20-mL vial
zidovudine (ZDV or AZT)	tablet	300 mg

Medicine	Pharmaceutical form type	Composition	Observation
efavirenz (EFV or EFZ)	capsule	50 mg	a
efavirenz (EFV or EFZ)	capsule	100 mg	a
efavirenz (EFV or EFZ)	capsule	200 mg	a
efavirenz (EFV or EFZ)	oral liquid	150 mg/5 ml	a
efavirenz (EFV or EFZ)	tablet	600 mg	a
nevirapine (NVP)	oral liquid	50 mg/5 ml
nevirapine (NVP)	tablet	200 mg

Selection of protease inhibitor(s) from the Model List will need to be determined by each country after consideration of international and national treatment guidelines and experience. Ritonavir is recommended for use in combination as a pharmacological booster, and not as an antiretroviral in its own right. All other protease inhibitors should be used in boosted forms (e.g. with ritonavir).

Medicine	Pharmaceutical form type	Composition	Observation
atazanavir	solid oral dosage form	100 mg (as sulfate)	a
atazanavir	solid oral dosage form	150 mg (as sulfate)	a
atazanavir	solid oral dosage form	300 mg (as sulfate)	a
indinavir (IDV)	solid oral dosage form	400 mg (as sulfate)
lopinavir + ritonavir (LPV/r)	capsule	133.3 mg + 33.3 mg
lopinavir + ritonavir (LPV/r)	oral liquid	400 mg + 100 mg/5 ml
lopinavir + ritonavir (LPV/r)	tablet (heat stable)	100 mg + 25 mg
lopinavir + ritonavir (LPV/r)	tablet (heat stable)	200 mg + 50 mg
ritonavir	oral liquid	400 mg/5 ml
ritonavir	solid oral dosage form	100 mg
ritonavir	tablet (heat stable)	25 mg
ritonavir	tablet (heat stable)	100 mg
saquinavir (SQV)	solid oral dosage form	200 mg (as mesilate)	a
saquinavir (SQV)	solid oral dosage form	500 mg (as mesilate)	a
efavirenz + emtricitabine + tenofovir	tablet	600 mg + 200 mg + 300 mg
emtricitabine + tenofovir	tablet	200 mg + 300 mg
lamivudine + nevirapine + stavudine	tablet	150 mg + 200 mg + 30 mg
lamivudine + nevirapine + stavudine	tablet (dispersible)	30 mg + 50 mg + 6 mg	c2
lamivudine + nevirapine + stavudine	tablet (dispersible)	60 mg + 100 mg + 12 mg	c2
lamivudine + nevirapine + zidovudine	tablet	30 mg + 50 mg + 60 mg	c2
lamivudine + nevirapine + zidovudine	tablet	150 mg + 200 mg + 300 mg
lamivudine + zidovudine	tablet	30 mg + 60 mg	c2
lamivudine + zidovudine	tablet	150 mg + 300 mg

Medicine	Pharmaceutical form type	Composition
oseltamivir	capsule	30 mg (as phosphate)
oseltamivir	capsule	45 mg (as phosphate)
oseltamivir	capsule	75 mg (as phosphate)
oseltamivir	oral powder	12 mg/mL
ribavirin	injection for intravenous administration	800 mg in 10-ml phosphate buffer solution
ribavirin	injection for intravenous administration	1 g in 10-ml phosphate buffer solution
ribavirin	solid oral dosage form	200 mg
ribavirin	solid oral dosage form	400 mg
ribavirin	solid oral dosage form	600 mg

Medicine	Pharmaceutical form type	Composition	Observation
diloxanide	tablet	500 mg (furoate)
metronidazole	Injection	500 mg in 100-mL vial	e
metronidazole	oral liquid	200 mg (as benzoate)/5 mL	e
metronidazole	tablet	200 mg to 500 mg	e

Medicine	Pharmaceutical form type	Composition
amphotericin B	Powder for injection	50 mg in vial
miltefosine	solid oral dosage form	10 mg
miltefosine	solid oral dosage form	50 mg
paromomycin	solution for intramuscular injection	750 mg of paromomycin base (as the sulfate)
sodium stibogluconate	Injection	100 mg/ml, 1 vial = 30 ml
meglumine antimoniate	Injection	30%, equivalent to approximately 8.1% antimony (pentavalent) in 5-ml ampoule

Medicines for the treatment of P. falciparum malaria cases should be used in combination. The list currently recommends combinations according to treatment guidelines. The Committee recognizes that not all of these FDCs exist and encourages their development and rigorous testing. The Committee also encourages development and testing of rectal dosage formulations.

Medicine	Pharmaceutical form type	Composition	Observation
amodiaquine	tablet	153 mg (as hydrochloride)
amodiaquine	tablet	200 mg (as hydrochloride)
artemether	Oily injection	80 mg/ml in 1-ml ampoule
artemether + lumefantrine	tablet	20 mg + 120 mg
artemether + lumefantrine	tablet (dispersible)	20 mg + 120 mg	c2
artesunate	Injection	ampoules, containing 60 mg anhydrous artesunic acid with a separate ampoule of 5% sodium bicarbonate solution
artesunate	rectal dosage form	50 mg capsules	c2
artesunate	rectal dosage form	200 mg capsules	c2
artesunate	tablet	50 mg
artesunate + amodiaquine	tablet	25 mg + 67.5 mg
artesunate + amodiaquine	tablet	50 mg + 135 mg
artesunate + amodiaquine	tablet	100 mg + 270 mg
chloroquine	oral liquid	50 mg (as phosphate or sulfate)/5 ml
chloroquine	tablet	100 mg (as phosphate or sulfate)
chloroquine	tablet	150 mg (as phosphate or sulfate)
doxycycline	capsule	100 mg (as hydrochloride or hyclate)
doxycycline	tablet (dispersible)	100 mg (as monohydrate)
mefloquine	tablet	250 mg (hydrochloride)
primaquine	tablet	7.5 mg (as diphosphate)
primaquine	tablet	15 mg (as diphosphate)
quinine	Injection	300 mg quinine hydrochloride/mL in 2-mL ampoule
quinine	tablet	300 mg (quinine sulfate)
quinine	tablet	300 mg (quinine bisulfate)
sulfadoxine + pyrimethamine	tablet	500 mg + 25 mg

Medicine	Pharmaceutical form type	Composition
mefloquine	tablet	250 mg (hydrochloride)
proguanil	tablet	100 mg (as hydrochloride)
chloroquine	oral liquid	50 mg (as phosphate or sulfate)/5 ml
chloroquine	tablet	150 mg (as phosphate or sulfate)
doxycycline	solid oral dosage form	100 mg (as hydrochloride or hyclate)

Medicine	Pharmaceutical form type	Composition	Observation
sulfamethoxazole + trimethoprim	tablet	400 mg + 80 mg	c2
sulfamethoxazole + trimethoprim	oral liquid	200 mg + 40 mg/5 mL	c2
sulfamethoxazole + trimethoprim	tablet	100 mg + 20 mg
sulfamethoxazole + trimethoprim	Injection	80 mg + 16 mg/mL in 5-mL ampoule
sulfamethoxazole + trimethoprim	Injection	80 mg + 16 mg/mL in 10-mL ampoule
sulfamethoxazole + trimethoprim	oral liquid	200 mg + 40 mg/5 mL	c2
pyrimethamine	tablet	25 mg
sulfadiazine	tablet	500 mg

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
pentamidine	tablet	300 mg (as isethionate)
pentamidine	tablet	200 mg (as isethionate)

Medicine	Pharmaceutical form type	Composition	Observation
pentamidine	Powder for injection	200 mg (isetionate) in vial
suramin sodium	Powder for injection	1 g in vial

Medicine	Pharmaceutical form type	Composition
eflornithine	Injection	200 mg (hydrochloride)/ml in 100-ml bottle
melarsoprol	Injection	3.6% solution, 5-ml ampoule (180 mg of active compound)
nifurtimox	tablet	120 mg

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
melarsoprol	Injection	3.6% solution, 5-ml ampoule (180 mg of active compound)	c1

Medicine	Pharmaceutical form type	Composition
benznidazole	tablet	100 mg
nifurtimox	tablet	30 mg
nifurtimox	tablet	120 mg
nifurtimox	tablet	250 mg

07. Antimigraine medicines

Medicine	Pharmaceutical form type	Composition	Observation
acetylsalicylic acid	tablet	300 mg to 500 mg
ibuprofen	tablet	200 mg	c2
ibuprofen	tablet	400 mg	c2
paracetamol	oral liquid	125 mg/5 ml	c2
paracetamol	tablet	300 mg to 500 mg

Medicine	Pharmaceutical form type	Composition	Observation
propranolol	tablet	20 mg (hydrochloride)	e
propranolol	tablet	40 mg (hydrochloride)	e

08. Antineoplastic, immunosuppressives and medicines used in Palliative care

Medicine	Pharmaceutical form type	Composition	Observation

Complementary list

Medicine	Pharmaceutical form type	Composition
azathioprine	Powder for injection	100 mg (as sodium salt) in vial
azathioprine	tablet (scored)	50 mg
ciclosporin	capsule	25 mg
ciclosporin	concentrate for injection	50 mg/ml in 1-ml ampoule

Medicine	Pharmaceutical form type	Composition	Observation

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
allopurinol	tablet	100 mg	c1
allopurinol	tablet	300 mg	c1
asparaginase	Powder for injection	10 000 IU in vial
bleomycin	Powder for injection	15 mg (as sulfate) in vial
calcium folinate	Injection	3 mg/mL in 10-mL ampoule
calcium folinate	tablet	15 mg
carboplatin	Injection	50 mg/5 mL	e
carboplatin	Injection	150 mg/15 mL	e
carboplatin	Injection	450 mg/45 mL	e
carboplatin	Injection	600 mg/60 mL	e
chlorambucil	tablet	2 mg
cyclophosphamide	Powder for injection	500 mg in vial
cyclophosphamide	tablet	25 mg
cytarabine	Powder for injection	100 mg in vial
dacarbazine	Powder for injection	100 mg in vial
dactinomycin	Powder for injection	500 mcg in vial
daunorubicin	Powder for injection	50 mg (hydrochloride) in vial
docetaxel	Injection	20 mg/ml
docetaxel	Injection	40 mg/mL
doxorubicin	Powder for injection	10 mg (hydrochloride) in vial
doxorubicin	Powder for injection	50 mg (hydrochloride) in vial
etoposide	capsule	100 mg
etoposide	Injection	20 mg/mL in 5-mL ampoule
fluorouracil	Injection	50 mg/ml in 5-ml ampoule
hydroxycarbamide	solid oral dosage form	200 mg
hydroxycarbamide	solid oral dosage form	250 mg
hydroxycarbamide	solid oral dosage form	300 mg
hydroxycarbamide	solid oral dosage form	400 mg
hydroxycarbamide	solid oral dosage form	500 mg
hydroxycarbamide	solid oral dosage form	1 g
ifosfamide	Powder for injection	1 g in vial
ifosfamide	Powder for injection	2 g in vial
mercaptopurine	tablet	50 mg
mesna	Injection	100 mg/ml in 4-ml ampoules
mesna	Injection	100 mg/ml in 10-ml ampoules
mesna	tablet	400 mg
mesna	tablet	600 mg
methotrexate	Powder for injection	50 mg (as sodium salt) in vial
methotrexate	tablet	2.5 mg (as sodium salt)
paclitaxel	Powder for injection	6 mg/ml
procarbazine	capsule	50 mg (as hydrochloride)
thioguanine	solid oral dosage form	40 mg	c1
vinblastine	Powder for injection	10 mg (sulfate) in vial
vincristine	Powder for injection	1 mg (sulfate) in vial
vincristine	Powder for injection	5 mg (sulfate) in vial

Medicine	Pharmaceutical form type	Composition	Observation

Complementary list

Medicine	Pharmaceutical form type	Composition	Observation
dexamethasone	Injection